Gao FB - Search Results

1

Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.

Loveland AB, Svidritskiy E, Susorov D, Lee S, Park A, Zvornicanin S, Demo G, Gao FB, Korostelev AA. Loveland AB, et al. Among authors: gao fb. Nat Commun. 2022 May 19;13(1):2776. doi: 10.1038/s41467-022-30418-0. Nat Commun. 2022. PMID: 35589706 Free PMC article.

2

The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila.

Li Z, Lu Y, Xu XL, Gao FB. Li Z, et al. Among authors: gao fb. Hum Mol Genet. 2013 Jan 15;22(2):218-25. doi: 10.1093/hmg/dds420. Epub 2012 Oct 5. Hum Mol Genet. 2013. PMID: 23042786 Free PMC article.

3

Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.

Almeida S, Gascon E, Tran H, Chou HJ, Gendron TF, Degroot S, Tapper AR, Sellier C, Charlet-Berguerand N, Karydas A, Seeley WW, Boxer AL, Petrucelli L, Miller BL, Gao FB. Almeida S, et al. Among authors: gao fb. Acta Neuropathol. 2013 Sep;126(3):385-99. doi: 10.1007/s00401-013-1149-y. Epub 2013 Jul 9. Acta Neuropathol. 2013. PMID: 23836290 Free PMC article.

4

The emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disorders.

Gascon E, Gao FB. Gascon E, et al. Among authors: gao fb. J Neurogenet. 2014 Mar-Jun;28(1-2):30-40. doi: 10.3109/01677063.2013.876021. Epub 2014 Feb 10. J Neurogenet. 2014. PMID: 24506814 Free PMC article. Review.

5

FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions.

Yang D, Abdallah A, Li Z, Lu Y, Almeida S, Gao FB. Yang D, et al. Among authors: gao fb. Acta Neuropathol. 2015 Oct;130(4):525-35. doi: 10.1007/s00401-015-1448-6. Epub 2015 Jun 2. Acta Neuropathol. 2015. PMID: 26031661 Free PMC article.

6

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.

Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. Freibaum BD, et al. Among authors: gao fb. Nature. 2015 Sep 3;525(7567):129-33. doi: 10.1038/nature14974. Epub 2015 Aug 26. Nature. 2015. PMID: 26308899 Free PMC article.

7

Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS.

Tran H, Almeida S, Moore J, Gendron TF, Chalasani U, Lu Y, Du X, Nickerson JA, Petrucelli L, Weng Z, Gao FB. Tran H, et al. Among authors: gao fb. Neuron. 2015 Sep 23;87(6):1207-1214. doi: 10.1016/j.neuron.2015.09.015. Neuron. 2015. PMID: 26402604 Free PMC article.

8

Lost & found: C9ORF72 and the autophagy pathway in ALS/FTD.

Almeida S, Gao FB. Almeida S, et al. Among authors: gao fb. EMBO J. 2016 Jun 15;35(12):1251-3. doi: 10.15252/embj.201694578. Epub 2016 May 6. EMBO J. 2016. PMID: 27154207 Free PMC article.

9

Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.

Lopez-Gonzalez R, Lu Y, Gendron TF, Karydas A, Tran H, Yang D, Petrucelli L, Miller BL, Almeida S, Gao FB. Lopez-Gonzalez R, et al. Among authors: gao fb. Neuron. 2016 Oct 19;92(2):383-391. doi: 10.1016/j.neuron.2016.09.015. Epub 2016 Oct 6. Neuron. 2016. PMID: 27720481 Free PMC article.

10

Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.

Yin S, Lopez-Gonzalez R, Kunz RC, Gangopadhyay J, Borufka C, Gygi SP, Gao FB, Reed R. Yin S, et al. Among authors: gao fb. Cell Rep. 2017 Jun 13;19(11):2244-2256. doi: 10.1016/j.celrep.2017.05.056. Cell Rep. 2017. PMID: 28614712 Free PMC article.

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