Activation of pregnane X receptor induces atherogenic lipids and PCSK9 by a SREBP2-mediated mechanism.
Karpale M, Käräjämäki AJ, Kummu O, Gylling H, Hyötyläinen T, Orešič M, Tolonen A, Hautajärvi H, Savolainen MJ, Ala-Korpela M, Hukkanen J, Hakkola J.
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Br J Pharmacol. 2021 Jun;178(12):2461-2481. doi: 10.1111/bph.15433. Epub 2021 May 14.
Br J Pharmacol. 2021.
PMID: 33687065
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