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Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival.
Cosgrove CM, Cohn DE, Hampel H, Frankel WL, Jones D, McElroy JP, Suarez AA, Zhao W, Chen W, Salani R, Copeland LJ, O'Malley DM, Fowler JM, Yilmaz A, Chassen AS, Pearlman R, Goodfellow PJ, Backes FJ. Cosgrove CM, et al. Gynecol Oncol. 2017 Sep;146(3):588-595. doi: 10.1016/j.ygyno.2017.07.003. Epub 2017 Jul 11. Gynecol Oncol. 2017. PMID: 28709704 Free PMC article.
Imaging biomarkers of adiposity and sarcopenia as potential predictors for overall survival among patients with endometrial cancer treated with bevacizumab.
Gillen J, Mills KA, Dvorak J, Zheng B, Thai T, Salani R, Cosgrove CM, Davidson B, Thaker PH, Moore KN. Gillen J, et al. Among authors: cosgrove cm. Gynecol Oncol Rep. 2019 Oct 5;30:100502. doi: 10.1016/j.gore.2019.100502. eCollection 2019 Nov. Gynecol Oncol Rep. 2019. PMID: 31720357 Free PMC article.
Double somatic mismatch repair gene pathogenic variants as common as Lynch syndrome among endometrial cancer patients.
Hampel H, Pearlman R, de la Chapelle A, Pritchard CC, Zhao W, Jones D, Yilmaz A, Chen W, Frankel WL, Suarez AA, Cosgrove C, Backes F, Copeland L, Fowler J, O'Malley D, Salani R, McElroy JP, Stanich PP, Goodfellow P, Cohn DE. Hampel H, et al. Gynecol Oncol. 2021 Jan;160(1):161-168. doi: 10.1016/j.ygyno.2020.10.012. Epub 2020 Oct 21. Gynecol Oncol. 2021. PMID: 33393477 Free PMC article.
Mutated p53 portends improvement in outcomes when bevacizumab is combined with chemotherapy in advanced/recurrent endometrial cancer: An NRG Oncology study.
Leslie KK, Filiaci VL, Mallen AR, Thiel KW, Devor EJ, Moxley K, Richardson D, Mutch D, Secord AA, Tewari KS, McDonald ME, Mathews C, Cosgrove C, Dewdney S, Casablanca Y, Jackson A, Rose PG, Zhou X, McHale M, Lankes H, Levine DA, Aghajanian C. Leslie KK, et al. Gynecol Oncol. 2021 Apr;161(1):113-121. doi: 10.1016/j.ygyno.2021.01.025. Epub 2021 Feb 2. Gynecol Oncol. 2021. PMID: 33541735 Free PMC article.
Phase I evaluation of lenvatinib and weekly paclitaxel in patients with recurrent endometrial, ovarian, fallopian tube, or primary peritoneal Cancer.
Backes FJ, Wei L, Chen M, Hill K, Dzwigalski K, Poi M, Phelps M, Salani R, Copeland LJ, Fowler JM, Cohn DE, Bixel K, Cosgrove C, Hays J, O'Malley D. Backes FJ, et al. Gynecol Oncol. 2021 Sep;162(3):619-625. doi: 10.1016/j.ygyno.2021.06.032. Epub 2021 Jul 14. Gynecol Oncol. 2021. PMID: 34272090 Clinical Trial.
Endometrial Cancer: Who Lives, Who Dies, Can We Improve Their Story?
Cosgrove CM, Backes FJ, O'Malley D, Bixel KL, Suarez AA, Fowler JM, Copeland LJ, Goodfellow PJ, Cohn DE. Cosgrove CM, et al. Oncologist. 2021 Dec;26(12):1044-1051. doi: 10.1002/onco.13934. Epub 2021 Aug 25. Oncologist. 2021. PMID: 34402130 Free PMC article.
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