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Hexamerization of Anti-SARS CoV IgG1 Antibodies Improves Neutralization Capacity.
Pande K, Hollingsworth SA, Sam M, Gao Q, Singh S, Saha A, Vroom K, Ma XS, Brazell T, Gorman D, Chen SJ, Raoufi F, Bailly M, Grandy D, Sathiyamoorthy K, Zhang L, Thompson R, Cheng AC, Fayadat-Dilman L, Geierstanger BH, Kingsley LJ. Pande K, et al. Among authors: cheng ac. Front Immunol. 2022 May 4;13:864775. doi: 10.3389/fimmu.2022.864775. eCollection 2022. Front Immunol. 2022. PMID: 35603164 Free PMC article.
Discovery of a new class of integrin antibodies for fibrosis.
Zhang J, Wang T, Saigal A, Johnson J, Morrisson J, Tabrizifard S, Hollingsworth SA, Eddins MJ, Mao W, O'Neill K, Garcia-Calvo M, Carballo-Jane E, Liu D, Ham T, Zhou Q, Dong W, Meng HW, Hicks J, Cai TQ, Akiyama T, Pinto S, Cheng AC, Greshock T, Marquis JC, Ren Z, Talukdar S, Shaheen HH, Handa M. Zhang J, et al. Among authors: cheng ac. Sci Rep. 2021 Jan 22;11(1):2118. doi: 10.1038/s41598-021-81253-0. Sci Rep. 2021. PMID: 33483531 Free PMC article.
Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants.
Hollingsworth SA, Noland CL, Vroom K, Saha A, Sam M, Gao Q, Zhou H, Grandy DU, Singh S, Wen Z, Warren C, Ma XS, Malashock D, Galli J, Go G, Eddins M, Mayhood T, Sathiyamoorthy K, Fridman A, Raoufi F, Gomez-Llorente Y, Patridge A, Tang Y, Chen SJ, Bailly M, Ji C, Kingsley LJ, Cheng AC, Geierstanger BH, Gorman DM, Zhang L, Pande K. Hollingsworth SA, et al. Among authors: cheng ac. Sci Rep. 2023 Aug 22;13(1):13668. doi: 10.1038/s41598-023-40919-7. Sci Rep. 2023. PMID: 37608223 Free PMC article.
Design and Optimization of Selectivity-Tunable Toll-like Receptor 7/8 Agonists as Novel Antibody-Drug Conjugate Payloads.
Patel AM, Willingham A, Cheng AC, Tomazela D, Bowman E, Kofman E, Zhang F, Bao J, Sanzone JR, Choy JW, Flygare JA, Han JH, Pradhan K, Kieffer M, Chernyak N, Akbari P, Liu P, Mehmood R, Naravula S, Hollingsworth SA, Bhagwat B, Lang SB, Seganish WM. Patel AM, et al. Among authors: cheng ac. J Med Chem. 2024 Sep 12;67(17):15756-15779. doi: 10.1021/acs.jmedchem.4c01384. Epub 2024 Aug 22. J Med Chem. 2024. PMID: 39172064
Deep learning approaches in predicting ADMET properties.
Cáceres EL, Tudor M, Cheng AC. Cáceres EL, et al. Among authors: cheng ac. Future Med Chem. 2020 Nov;12(22):1995-1999. doi: 10.4155/fmc-2020-0259. Epub 2020 Oct 30. Future Med Chem. 2020. PMID: 33124448 Free article. Review. No abstract available.
898 results