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Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus.
Patrick DM, de la Visitación N, Krishnan J, Chen W, Ormseth MJ, Stein CM, Davies SS, Amarnath V, Crofford LJ, Williams JM, Zhao S, Smart CD, Dikalov S, Dikalova A, Xiao L, Van Beusecum JP, Ao M, Fogo AB, Kirabo A, Harrison DG. Patrick DM, et al. Among authors: amarnath v. JCI Insight. 2022 Jul 8;7(13):e136678. doi: 10.1172/jci.insight.136678. JCI Insight. 2022. PMID: 35608913 Free PMC article.
Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension.
Prinsen JK, Kannankeril PJ, Sidorova TN, Yermalitskaya LV, Boutaud O, Zagol-Ikapitte I, Barnett JV, Murphy MB, Subati T, Stark JM, Christopher IL, Jafarian-Kerman SR, Saleh MA, Norlander AE, Loperena R, Atkinson JB, Fogo AB, Luther JM, Amarnath V, Davies SS, Kirabo A, Madhur MS, Harrison DG, Murray KT. Prinsen JK, et al. Among authors: amarnath v. JACC Basic Transl Sci. 2020 May 27;5(6):602-615. doi: 10.1016/j.jacbts.2020.04.004. eCollection 2020 Jun. JACC Basic Transl Sci. 2020. PMID: 32613146 Free PMC article.
Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation.
Mayorov V, Uchakin P, Amarnath V, Panov AV, Bridges CC, Uzhachenko R, Zackert B, Moore CS, Davies S, Dikalova A, Dikalov S. Mayorov V, et al. Among authors: amarnath v. Redox Biol. 2019 Sep;26:101300. doi: 10.1016/j.redox.2019.101300. Epub 2019 Aug 14. Redox Biol. 2019. PMID: 31437812 Free PMC article.
Mitochondrial Isolevuglandins Contribute to Vascular Oxidative Stress and Mitochondria-Targeted Scavenger of Isolevuglandins Reduces Mitochondrial Dysfunction and Hypertension.
Dikalova A, Mayorov V, Xiao L, Panov A, Amarnath V, Zagol-Ikapitte I, Vergeade A, Ao M, Yermalitsky V, Nazarewicz RR, Boutaud O, Lopez MG, Billings FT 4th, Davies S, Roberts LJ 2nd, Harrison DG, Dikalov S. Dikalova A, et al. Among authors: amarnath v. Hypertension. 2020 Dec;76(6):1980-1991. doi: 10.1161/HYPERTENSIONAHA.120.15236. Epub 2020 Oct 5. Hypertension. 2020. PMID: 33012204 Free PMC article.
Isolevuglandin-Modified Cardiac Proteins Drive CD4+ T-Cell Activation in the Heart and Promote Cardiac Dysfunction.
Ngwenyama N, Kirabo A, Aronovitz M, Velázquez F, Carrillo-Salinas F, Salvador AM, Nevers T, Amarnath V, Tai A, Blanton RM, Harrison DG, Alcaide P. Ngwenyama N, et al. Among authors: amarnath v. Circulation. 2021 Mar 23;143(12):1242-1255. doi: 10.1161/CIRCULATIONAHA.120.051889. Epub 2021 Jan 19. Circulation. 2021. PMID: 33463362 Free PMC article.
113 results