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Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus.
Patrick DM, de la Visitación N, Krishnan J, Chen W, Ormseth MJ, Stein CM, Davies SS, Amarnath V, Crofford LJ, Williams JM, Zhao S, Smart CD, Dikalov S, Dikalova A, Xiao L, Van Beusecum JP, Ao M, Fogo AB, Kirabo A, Harrison DG. Patrick DM, et al. Among authors: xiao l. JCI Insight. 2022 Jul 8;7(13):e136678. doi: 10.1172/jci.insight.136678. JCI Insight. 2022. PMID: 35608913 Free PMC article.
Critical role of Interleukin 21 and T follicular helper cells in hypertension and vascular dysfunction.
Dale BL, Pandey AK, Chen Y, Smart CD, Laroumanie F, Ao M, Xiao L, Dikalova AE, Dikalov SI, Elijovich F, Foss JD, Barbaro NR, Van Beusecum JP, Deger SM, Alsouqi A, Itani HA, Norlander AE, Alexander MR, Zhao S, Ikizler TA, Algood HMS, Madhur MS. Dale BL, et al. Among authors: xiao l. JCI Insight. 2019 Apr 23;5(11):e129278. doi: 10.1172/jci.insight.129278. JCI Insight. 2019. PMID: 31013256 Free PMC article.
High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.
Ferguson JF, Aden LA, Barbaro NR, Van Beusecum JP, Xiao L, Simmons AJ, Warden C, Pasic L, Himmel LE, Washington MK, Revetta FL, Zhao S, Kumaresan S, Scholz MB, Tang Z, Chen G, Reilly MP, Kirabo A. Ferguson JF, et al. Among authors: xiao l. JCI Insight. 2019 Jun 4;5(13):e126241. doi: 10.1172/jci.insight.126241. JCI Insight. 2019. PMID: 31162138 Free PMC article.
LNK deficiency promotes acute aortic dissection and rupture.
Laroumanie F, Korneva A, Bersi MR, Alexander MR, Xiao L, Zhong X, Van Beusecum JP, Chen Y, Saleh MA, McMaster WG, Gavulic KA, Dale BL, Zhao S, Guo Y, Shyr Y, Perrien DS, Cox NJ, Curci JA, Humphrey JD, Madhur MS. Laroumanie F, et al. Among authors: xiao l. JCI Insight. 2018 Oct 18;3(20):e122558. doi: 10.1172/jci.insight.122558. JCI Insight. 2018. PMID: 30333305 Free PMC article.
High Salt Activates CD11c+ Antigen-Presenting Cells via SGK (Serum Glucocorticoid Kinase) 1 to Promote Renal Inflammation and Salt-Sensitive Hypertension.
Van Beusecum JP, Barbaro NR, McDowell Z, Aden LA, Xiao L, Pandey AK, Itani HA, Himmel LE, Harrison DG, Kirabo A. Van Beusecum JP, et al. Among authors: xiao l. Hypertension. 2019 Sep;74(3):555-563. doi: 10.1161/HYPERTENSIONAHA.119.12761. Epub 2019 Jul 8. Hypertension. 2019. PMID: 31280647 Free PMC article.
Inflammation in Hypertension.
Xiao L, Harrison DG. Xiao L, et al. Can J Cardiol. 2020 May;36(5):635-647. doi: 10.1016/j.cjca.2020.01.013. Epub 2020 Jan 24. Can J Cardiol. 2020. PMID: 32389337 Free PMC article. Review.
Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation.
Ruggeri Barbaro N, Van Beusecum J, Xiao L, do Carmo L, Pitzer A, Loperena R, Foss JD, Elijovich F, Laffer CL, Montaniel KR, Galindo CL, Chen W, Ao M, Mernaugh RL, Alsouqi A, Ikizler TA, Fogo AB, Moreno H, Zhao S, Davies SS, Harrison DG, Kirabo A. Ruggeri Barbaro N, et al. Among authors: xiao l. Cardiovasc Res. 2021 Apr 23;117(5):1358-1371. doi: 10.1093/cvr/cvaa207. Cardiovasc Res. 2021. PMID: 33038226 Free PMC article.
Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension.
Van Beusecum JP, Barbaro NR, Smart CD, Patrick DM, Loperena R, Zhao S, de la Visitacion N, Ao M, Xiao L, Shibao CA, Harrison DG. Van Beusecum JP, et al. Among authors: xiao l. Circ Res. 2021 Nov 12;129(11):975-991. doi: 10.1161/CIRCRESAHA.121.319643. Epub 2021 Sep 27. Circ Res. 2021. PMID: 34565181 Free PMC article.
9,837 results