Wong H - Search Results

1

RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer's disease, and normative aging.

Wong H, Buck JM, Borski C, Pafford JT, Keller BN, Milstead RA, Hanson JL, Stitzel JA, Hoeffer CA. Wong H, et al. J Neurodev Disord. 2022 May 24;14(1):33. doi: 10.1186/s11689-022-09444-y. J Neurodev Disord. 2022. PMID: 35610565 Free PMC article.

2

The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling.

Hoeffer CA, Dey A, Sachan N, Wong H, Patterson RJ, Shelton JM, Richardson JA, Klann E, Rothermel BA. Hoeffer CA, et al. Among authors: wong h. J Neurosci. 2007 Nov 28;27(48):13161-72. doi: 10.1523/JNEUROSCI.3974-07.2007. J Neurosci. 2007. PMID: 18045910 Free PMC article.

3

Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior.

Hoeffer CA, Tang W, Wong H, Santillan A, Patterson RJ, Martinez LA, Tejada-Simon MV, Paylor R, Hamilton SL, Klann E. Hoeffer CA, et al. Among authors: wong h. Neuron. 2008 Dec 10;60(5):832-45. doi: 10.1016/j.neuron.2008.09.037. Neuron. 2008. PMID: 19081378 Free PMC article.

4

Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.

Suvrathan A, Hoeffer CA, Wong H, Klann E, Chattarji S. Suvrathan A, et al. Among authors: wong h. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11591-6. doi: 10.1073/pnas.1002262107. Epub 2010 Jun 7. Proc Natl Acad Sci U S A. 2010. PMID: 20534533 Free PMC article.

5

Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease.

Ma T, Hoeffer CA, Capetillo-Zarate E, Yu F, Wong H, Lin MT, Tampellini D, Klann E, Blitzer RD, Gouras GK. Ma T, et al. Among authors: wong h. PLoS One. 2010 Sep 20;5(9):e12845. doi: 10.1371/journal.pone.0012845. PLoS One. 2010. PMID: 20862226 Free PMC article.

6

Fecal corticosterone levels in RCAN1 mutant mice.

Rakowski-Anderson T, Wong H, Rothermel B, Cain P, Lavilla C, Pullium JK, Hoeffer C. Rakowski-Anderson T, et al. Among authors: wong h. Comp Med. 2012 Apr;62(2):87-94. Comp Med. 2012. PMID: 22546913 Free PMC article.

7

Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation.

Hoeffer CA, Santini E, Ma T, Arnold EC, Whelan AM, Wong H, Pierre P, Pelletier J, Klann E. Hoeffer CA, et al. Among authors: wong h. J Neurophysiol. 2013 Jan;109(1):68-76. doi: 10.1152/jn.00342.2012. Epub 2012 Oct 10. J Neurophysiol. 2013. PMID: 23054596 Free PMC article.

8

Regulator of calcineurin 1 modulates expression of innate anxiety and anxiogenic responses to selective serotonin reuptake inhibitor treatment.

Hoeffer CA, Wong H, Cain P, Levenga J, Cowansage KK, Choi Y, Davy C, Majmundar N, McMillan DR, Rothermel BA, Klann E. Hoeffer CA, et al. Among authors: wong h. J Neurosci. 2013 Oct 23;33(43):16930-44. doi: 10.1523/JNEUROSCI.3513-12.2013. J Neurosci. 2013. PMID: 24155299 Free PMC article.

9

Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments.

Levenga J, Krishnamurthy P, Rajamohamedsait H, Wong H, Franke TF, Cain P, Sigurdsson EM, Hoeffer CA. Levenga J, et al. Among authors: wong h. Acta Neuropathol Commun. 2013 Jul 11;1:34. doi: 10.1186/2051-5960-1-34. Acta Neuropathol Commun. 2013. PMID: 24252661 Free PMC article.

10

RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer's disease.

Wong H, Levenga J, Cain P, Rothermel B, Klann E, Hoeffer C. Wong H, et al. Acta Neuropathol. 2015 Dec;130(6):829-43. doi: 10.1007/s00401-015-1499-8. Epub 2015 Oct 24. Acta Neuropathol. 2015. PMID: 26497675 Free PMC article.

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