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Page 1
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad.
Mayère C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, Bellido-Carreras N, Sararols P, Reeves R, Greenaway S, Simon M, Siggers P, Condrea D, Kühne F, Gantar I, Tang F, Stévant I, Batti L, Ghyselinck NB, Wilhelm D, Greenfield A, Capel B, Chaboissier MC, Nef S. Mayère C, et al. Among authors: siggers p. Sci Adv. 2022 May 27;8(21):eabm0972. doi: 10.1126/sciadv.abm0972. Epub 2022 May 25. Sci Adv. 2022. PMID: 35613264 Free PMC article.
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.
Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A. Bogani D, et al. Among authors: siggers p. PLoS Biol. 2009 Sep;7(9):e1000196. doi: 10.1371/journal.pbio.1000196. Epub 2009 Sep 15. PLoS Biol. 2009. PMID: 19753101 Free PMC article.
ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.
Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes DT, Suzuki M, Burdine RD, Cong F, Koo BK, Clevers H, Stévant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A. Harris A, et al. Among authors: siggers p. Proc Natl Acad Sci U S A. 2018 May 22;115(21):5474-5479. doi: 10.1073/pnas.1801223115. Epub 2018 May 7. Proc Natl Acad Sci U S A. 2018. PMID: 29735715 Free PMC article.
Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development.
Grimmond S, Van Hateren N, Siggers P, Arkell R, Larder R, Soares MB, de Fatima Bonaldo M, Smith L, Tymowska-Lalanne Z, Wells C, Greenfield A. Grimmond S, et al. Among authors: siggers p. Hum Mol Genet. 2000 Jun 12;9(10):1553-60. doi: 10.1093/hmg/9.10.1553. Hum Mol Genet. 2000. PMID: 10888606
Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2.
Field S, Riley KL, Grimes DT, Hilton H, Simon M, Powles-Glover N, Siggers P, Bogani D, Greenfield A, Norris DP. Field S, et al. Among authors: siggers p. Development. 2011 Mar;138(6):1131-42. doi: 10.1242/dev.058149. Epub 2011 Feb 9. Development. 2011. PMID: 21307093 Free PMC article.
27 results