Hamilton J - Search Results

1

Mitochondrial uncouplers induce proton leak by activating AAC and UCP1.

Bertholet AM, Natale AM, Bisignano P, Suzuki J, Fedorenko A, Hamilton J, Brustovetsky T, Kazak L, Garrity R, Chouchani ET, Brustovetsky N, Grabe M, Kirichok Y. Bertholet AM, et al. Among authors: hamilton j. Nature. 2022 Jun;606(7912):180-187. doi: 10.1038/s41586-022-04747-5. Epub 2022 May 25. Nature. 2022. PMID: 35614225 Free PMC article.

2

Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma.

Lakhter AJ, Hamilton J, Dagher PC, Mukkamala S, Hato T, Dong XC, Mayo LD, Harris RA, Shekhar A, Ivan M, Brustovetsky N, Naidu SR. Lakhter AJ, et al. Among authors: hamilton j. Oncotarget. 2014 Dec 30;5(24):12694-703. doi: 10.18632/oncotarget.3031. Oncotarget. 2014. PMID: 25587028 Free PMC article.

3

Ca(2+) handling in isolated brain mitochondria and cultured neurons derived from the YAC128 mouse model of Huntington's disease.

Pellman JJ, Hamilton J, Brustovetsky T, Brustovetsky N. Pellman JJ, et al. Among authors: hamilton j. J Neurochem. 2015 Aug;134(4):652-67. doi: 10.1111/jnc.13165. Epub 2015 Jun 4. J Neurochem. 2015. PMID: 25963273 Free PMC article.

4

Oxidative metabolism in YAC128 mouse model of Huntington's disease.

Hamilton J, Pellman JJ, Brustovetsky T, Harris RA, Brustovetsky N. Hamilton J, et al. Hum Mol Genet. 2015 Sep 1;24(17):4862-78. doi: 10.1093/hmg/ddv209. Epub 2015 Jun 3. Hum Mol Genet. 2015. PMID: 26041817 Free PMC article.

5

Oxidative metabolism and Ca2+ handling in isolated brain mitochondria and striatal neurons from R6/2 mice, a model of Huntington's disease.

Hamilton J, Pellman JJ, Brustovetsky T, Harris RA, Brustovetsky N. Hamilton J, et al. Hum Mol Genet. 2016 Jul 1;25(13):2762-2775. doi: 10.1093/hmg/ddw133. Epub 2016 Apr 30. Hum Mol Genet. 2016. PMID: 27131346 Free PMC article.

6

Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth.

Lakhter AJ, Hamilton J, Konger RL, Brustovetsky N, Broxmeyer HE, Naidu SR. Lakhter AJ, et al. Among authors: hamilton j. J Biol Chem. 2016 Oct 14;291(42):21869-21879. doi: 10.1074/jbc.M115.712166. Epub 2016 Aug 18. J Biol Chem. 2016. PMID: 27539851 Free PMC article.

7

Oxidative metabolism and Ca²⁺ handling in striatal mitochondria from YAC128 mice, a model of Huntington's disease.

Hamilton J, Brustovetsky T, Brustovetsky N. Hamilton J, et al. Neurochem Int. 2017 Oct;109:24-33. doi: 10.1016/j.neuint.2017.01.001. Epub 2017 Jan 3. Neurochem Int. 2017. PMID: 28062223 Free PMC article.

8

Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria.

Hamilton J, Brustovetsky T, Rysted JE, Lin Z, Usachev YM, Brustovetsky N. Hamilton J, et al. J Biol Chem. 2018 Oct 5;293(40):15652-15663. doi: 10.1074/jbc.RA118.002926. Epub 2018 Aug 28. J Biol Chem. 2018. PMID: 30154242 Free PMC article.

9

Mutant huntingtin fails to directly impair brain mitochondria.

Hamilton J, Brustovetsky T, Brustovetsky N. Hamilton J, et al. J Neurochem. 2019 Dec;151(6):716-731. doi: 10.1111/jnc.14852. Epub 2019 Oct 7. J Neurochem. 2019. PMID: 31418857 Free PMC article.

10

Energy Metabolism and Mitochondrial Superoxide Anion Production in Pre-symptomatic Striatal Neurons Derived from Human-Induced Pluripotent Stem Cells Expressing Mutant Huntingtin.

Hamilton J, Brustovetsky T, Sridhar A, Pan Y, Cummins TR, Meyer JS, Brustovetsky N. Hamilton J, et al. Mol Neurobiol. 2020 Feb;57(2):668-684. doi: 10.1007/s12035-019-01734-2. Epub 2019 Aug 21. Mol Neurobiol. 2020. PMID: 31435904

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