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CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells.
Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M, Castellví J, Wu G, Del Rio Estrada PM, González-Navarro M, Lynn K, King CT, Vemula S, Cox K, Wan Y, Li Q, Mounzer K, Kostman J, Frank I, Paiardini M, Hazuda D, Reyes-Terán G, Richman D, Howell B, Tebas P, Martinez-Picado J, Planelles V, Buzon MJ, Betts MR, Montaner LJ. Abdel-Mohsen M, et al. Sci Transl Med. 2018 Apr 18;10(437):eaar6759. doi: 10.1126/scitranslmed.aar6759. Sci Transl Med. 2018. PMID: 29669853 Free PMC article.
Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab.
Serra-Peinado C, Grau-Expósito J, Luque-Ballesteros L, Astorga-Gamaza A, Navarro J, Gallego-Rodriguez J, Martin M, Curran A, Burgos J, Ribera E, Raventós B, Willekens R, Torrella A, Planas B, Badía R, Garcia F, Castellví J, Genescà M, Falcó V, Buzon MJ. Serra-Peinado C, et al. Nat Commun. 2019 Aug 16;10(1):3705. doi: 10.1038/s41467-019-11556-4. Nat Commun. 2019. PMID: 31420544 Free PMC article.
Latency reversal agents affect differently the latent reservoir present in distinct CD4+ T subpopulations.
Grau-Expósito J, Luque-Ballesteros L, Navarro J, Curran A, Burgos J, Ribera E, Torrella A, Planas B, Badía R, Martin-Castillo M, Fernández-Sojo J, Genescà M, Falcó V, Buzon MJ. Grau-Expósito J, et al. PLoS Pathog. 2019 Aug 19;15(8):e1007991. doi: 10.1371/journal.ppat.1007991. eCollection 2019 Aug. PLoS Pathog. 2019. PMID: 31425551 Free PMC article.
Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa.
Cantero-Pérez J, Grau-Expósito J, Serra-Peinado C, Rosero DA, Luque-Ballesteros L, Astorga-Gamaza A, Castellví J, Sanhueza T, Tapia G, Lloveras B, Fernández MA, Prado JG, Solé-Sedeno JM, Tarrats A, Lecumberri C, Mañalich-Barrachina L, Centeno-Mediavilla C, Falcó V, Buzon MJ, Genescà M. Cantero-Pérez J, et al. Nat Commun. 2019 Oct 18;10(1):4739. doi: 10.1038/s41467-019-12732-2. Nat Commun. 2019. PMID: 31628331 Free PMC article.
Peripheral and lung resident memory T cell responses against SARS-CoV-2.
Grau-Expósito J, Sánchez-Gaona N, Massana N, Suppi M, Astorga-Gamaza A, Perea D, Rosado J, Falcó A, Kirkegaard C, Torrella A, Planas B, Navarro J, Suanzes P, Álvarez-Sierra D, Ayora A, Sansano I, Esperalba J, Andrés C, Antón A, Ramón Y Cajal S, Almirante B, Pujol-Borrell R, Falcó V, Burgos J, Buzón MJ, Genescà M. Grau-Expósito J, et al. Nat Commun. 2021 May 21;12(1):3010. doi: 10.1038/s41467-021-23333-3. Nat Commun. 2021. PMID: 34021148 Free PMC article.
Entrectinib-A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells.
Peralta-Garcia A, Torrens-Fontanals M, Stepniewski TM, Grau-Expósito J, Perea D, Ayinampudi V, Waldhoer M, Zimmermann M, Buzón MJ, Genescà M, Selent J. Peralta-Garcia A, et al. Among authors: grau exposito j. Int J Mol Sci. 2021 Dec 18;22(24):13592. doi: 10.3390/ijms222413592. Int J Mol Sci. 2021. PMID: 34948390 Free PMC article.
Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells.
Grau-Expósito J, Perea D, Suppi M, Massana N, Vergara A, Soler MJ, Trinite B, Blanco J, García-Pérez J, Alcamí J, Serrano-Mollar A, Rosado J, Falcó V, Genescà M, Buzon MJ. Grau-Expósito J, et al. PLoS Pathog. 2022 Jan 13;18(1):e1010171. doi: 10.1371/journal.ppat.1010171. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35025963 Free PMC article.
15 results