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ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression.
Quek H, Cuní-López C, Stewart R, Colletti T, Notaro A, Nguyen TH, Sun Y, Guo CC, Lupton MK, Roberts TL, Lim YC, Oikari LE, La Bella V, White AR. Quek H, et al. Among authors: cuni lopez c. J Neuroinflammation. 2022 Feb 28;19(1):58. doi: 10.1186/s12974-022-02421-1. J Neuroinflammation. 2022. PMID: 35227277 Free PMC article.
Altered Brain Endothelial Cell Phenotype from a Familial Alzheimer Mutation and Its Potential Implications for Amyloid Clearance and Drug Delivery.
Oikari LE, Pandit R, Stewart R, Cuní-López C, Quek H, Sutharsan R, Rantanen LM, Oksanen M, Lehtonen S, de Boer CM, Polo JM, Götz J, Koistinaho J, White AR. Oikari LE, et al. Among authors: cuni lopez c. Stem Cell Reports. 2020 May 12;14(5):924-939. doi: 10.1016/j.stemcr.2020.03.011. Epub 2020 Apr 9. Stem Cell Reports. 2020. PMID: 32275861 Free PMC article.
Alzheimer's disease brain endothelial-like cells reveal differential drug transporter expression and modulation by potentially therapeutic focused ultrasound.
Chaves JCS, Wasielewska JM, Cuní-López C, Rantanen LM, Lee S, Koistinaho J, White AR, Oikari LE. Chaves JCS, et al. Among authors: cuni lopez c. Neurotherapeutics. 2024 Jan;21(1):e00299. doi: 10.1016/j.neurot.2023.10.009. Epub 2023 Dec 19. Neurotherapeutics. 2024. PMID: 38241156 Free PMC article.