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Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.
Rubio C, Puerto M, García-Rodríquez JJ, Lu VB, García-Martínez I, Alén R, Sanmartín-Salinas P, Toledo-Lobo MV, Saiz J, Ruperez J, Barbas C, Menchén L, Gribble FM, Reimann F, Guijarro LG, Carrascosa JM, Valverde ÁM. Rubio C, et al. Among authors: alen r. Mol Metab. 2020 May;35:100954. doi: 10.1016/j.molmet.2020.01.018. Epub 2020 Feb 6. Mol Metab. 2020. PMID: 32244182 Free PMC article.
Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis.
Garcia-Martinez I, Alen R, Rada P, Valverde AM. Garcia-Martinez I, et al. Among authors: alen r. Front Med (Lausanne). 2020 Aug 11;7:395. doi: 10.3389/fmed.2020.00395. eCollection 2020. Front Med (Lausanne). 2020. PMID: 32850903 Free PMC article. Review.
Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition.
Ferreira V, Folgueira C, García-Altares M, Guillén M, Ruíz-Rosario M, DiNunzio G, Garcia-Martinez I, Alen R, Bookmeyer C, Jones JG, Cigudosa JC, López-Larrubia P, Correig-Blanchar X, Davis RJ, Sabio G, Rada P, Valverde ÁM. Ferreira V, et al. Among authors: alen r. Redox Biol. 2023 Jul;63:102741. doi: 10.1016/j.redox.2023.102741. Epub 2023 May 15. Redox Biol. 2023. PMID: 37230004 Free PMC article.
Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance.
Garcia-Martinez I, Alen R, Pereira L, Povo-Retana A, Astudillo AM, Hitos AB, Gomez-Hurtado I, Lopez-Collazo E, Boscá L, Francés R, Lizasoain I, Moro MÁ, Balsinde J, Izquierdo M, Valverde ÁM. Garcia-Martinez I, et al. Among authors: alen r. JHEP Rep. 2023 Apr 7;5(8):100756. doi: 10.1016/j.jhepr.2023.100756. eCollection 2023 Aug. JHEP Rep. 2023. PMID: 37360906 Free PMC article.
The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.
Valdecantos MP, Ruiz L, Folgueira C, Rada P, Gomez-Santos B, Solas M, Hitos AB, Field J, Francisco V, Escalona-Garrido C, Zagmutt S, Calderon-Dominguez M, Mera P, Garcia-Martinez I, Maymó-Masip E, Grajales D, Alen R, Mora A, Sáinz N, Vides-Urrestarazu I, Vilarrasa N, Arbones-Mainar JM, Zaragoza C, Moreno-Aliaga MJ, Aspichueta P, Fernández-Veledo S, Vendrell J, Serra D, Herrero L, Schreiber R, Zechner R, Sabio G, Hornigold D, Rondinone CM, Jermutus L, Grimsby J, Valverde ÁM. Valdecantos MP, et al. Among authors: alen r. Nat Commun. 2024 Nov 28;15(1):10342. doi: 10.1038/s41467-024-54080-w. Nat Commun. 2024. PMID: 39609390 Free PMC article.
Ablation of secreted phosphoprotein-1 in hepatocytes increases fatty acid oxidation and ameliorates alcohol-associated liver disease.
Das S, Subramaniyam N, Alén R, Komakula SSB, Song Z, Ge X, Han H, Desert R, Athavale D, Magdaleno F, Chen W, Barahona I, Lantvit D, Guzman G, Nieto N. Das S, et al. Among authors: alen r. Alcohol Clin Exp Res (Hoboken). 2024 May;48(5):781-794. doi: 10.1111/acer.15304. Epub 2024 Mar 19. Alcohol Clin Exp Res (Hoboken). 2024. PMID: 38503560
Analysis of Lipophilic Extractives from Fast Pyrolysis Bio-Oils.
Ohra-Aho T, Ghalibaf M, Alén R, Lindfors C, Oasmaa A. Ohra-Aho T, et al. Among authors: alen r. Energy Fuels. 2022 Jun 2;36(11):5797-5804. doi: 10.1021/acs.energyfuels.1c04325. Epub 2022 May 16. Energy Fuels. 2022. PMID: 35685649 Free PMC article.
42 results