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Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci.
Lima ARJ, Silva HGS, Poubel S, Rosón JN, de Lima LPO, Costa-Silva HM, Gonçalves CS, Galante PAF, Holetz F, Motta MCM, Silber AM, Elias MC, da Cunha JPC. Lima ARJ, et al. Among authors: silber am. Epigenetics Chromatin. 2022 Jun 1;15(1):22. doi: 10.1186/s13072-022-00450-x. Epigenetics Chromatin. 2022. PMID: 35650626 Free PMC article.
The Uptake of GABA in Trypanosoma cruzi.
Galvez Rojas RL, Ahn IY, Suárez Mantilla B, Sant'Anna C, Pral EM, Silber AM. Galvez Rojas RL, et al. Among authors: silber am. J Eukaryot Microbiol. 2015 Sep-Oct;62(5):629-36. doi: 10.1111/jeu.12219. Epub 2015 Apr 25. J Eukaryot Microbiol. 2015. PMID: 25851259
The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake.
Merli ML, Pagura L, Hernández J, Barisón MJ, Pral EM, Silber AM, Cricco JA. Merli ML, et al. Among authors: silber am. PLoS Negl Trop Dis. 2016 Jan 11;10(1):e0004359. doi: 10.1371/journal.pntd.0004359. eCollection 2016 Jan. PLoS Negl Trop Dis. 2016. PMID: 26752206 Free PMC article.
An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells.
Girard RM, Crispim M, Stolić I, Damasceno FS, Santos da Silva M, Pral EM, Elias MC, Bajić M, Silber AM. Girard RM, et al. Among authors: silber am. Antimicrob Agents Chemother. 2016 Sep 23;60(10):5867-77. doi: 10.1128/AAC.01595-15. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27431229 Free PMC article.
The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection.
Crispim M, Damasceno FS, Hernández A, Barisón MJ, Pretto Sauter I, Souza Pavani R, Santos Moura A, Pral EMF, Cortez M, Elias MC, Silber AM. Crispim M, et al. Among authors: silber am. PLoS Negl Trop Dis. 2018 Jan 10;12(1):e0006170. doi: 10.1371/journal.pntd.0006170. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29320490 Free PMC article.
109 results