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Combining variant detection and fragment length analysis improves detection of minimal residual disease in postsurgery circulating tumour DNA of stage II-IIIA NSCLC patients.
Vessies DCL, Schuurbiers MMF, van der Noort V, Schouten I, Linders TC, Lanfermeijer M, Ramkisoensing KL, Hartemink KJ, Monkhorst K, van den Heuvel MM, van den Broek D. Vessies DCL, et al. Among authors: linders tc. Mol Oncol. 2022 Jul;16(14):2719-2732. doi: 10.1002/1878-0261.13267. Epub 2022 Jun 27. Mol Oncol. 2022. PMID: 35674097 Free PMC article.
Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions.
Hummelink K, Muller M, Linders TC, van der Noort V, Nederlof PM, Baas P, Burgers S, Smit EF, Meijer GA, van den Heuvel MM, van den Broek D, Monkhorst K. Hummelink K, et al. Among authors: linders tc. ERJ Open Res. 2019 Mar 25;5(1):00016-2019. doi: 10.1183/23120541.00016-2019. eCollection 2019 Feb. ERJ Open Res. 2019. PMID: 30918895 Free PMC article.
An Automated Correction Algorithm (ALPACA) for ddPCR Data Using Adaptive Limit of Blank and Correction of False Positive Events Improves Specificity of Mutation Detection.
Vessies DCL, Linders TC, Lanfermeijer M, Ramkisoensing KL, van der Noort V, Schouten RD, Meijer GA, van den Heuvel MM, Monkhorst K, van den Broek D. Vessies DCL, et al. Among authors: linders tc. Clin Chem. 2021 Jul 6;67(7):959-967. doi: 10.1093/clinchem/hvab040. Clin Chem. 2021. PMID: 33842952
A Micro-Costing Framework for Circulating Tumor DNA Testing in Dutch Clinical Practice.
Kramer A, Schuuring E, Vessies DCL, van der Leest P, Geerlings MJ, Rozendal P, Lanfermeijer M, Linders TC, van Kempen LC, Fijneman RJA, Ligtenberg MJL, Meijer GA, van den Broek D, Retèl VP, Coupé VMH; COIN Consortium. Kramer A, et al. Among authors: linders tc. J Mol Diagn. 2023 Jan;25(1):36-45. doi: 10.1016/j.jmoldx.2022.10.004. Epub 2022 Nov 17. J Mol Diagn. 2023. PMID: 36402278 Free article.
High Prevalence of Chromosomal Rearrangements and LINE Retrotranspositions Detected in Formalin-Fixed, Paraffin-Embedded Colorectal Cancer Tissue.
Rubio-Alarcón C, Stelloo E, Vessies DCL, van 't Erve I, Mekkes NJ, Swennenhuis J, Lakbir S, van Bree EJ, Tijssen M, Delis-van Diemen P, Lanfermeijer M, Linders T, van den Broek D, Punt CJA, Heringa J, Meijer GA, Abeln S, Feitsma H, Fijneman RJA. Rubio-Alarcón C, et al. J Mol Diagn. 2024 Dec;26(12):1065-1080. doi: 10.1016/j.jmoldx.2024.08.004. Epub 2024 Sep 26. J Mol Diagn. 2024. PMID: 39332629 Free article.
Choice of tumour markers in patients with neuroendocrine tumours is dependent on the histological grade. A marker study of Chromogranin A, Neuron specific enolase, Progastrin-releasing peptide and cytokeratin fragments.
Korse CM, Taal BG, Vincent A, van Velthuysen ML, Baas P, Buning-Kager JC, Linders TC, Bonfrer JM. Korse CM, et al. Among authors: linders tc. Eur J Cancer. 2012 Mar;48(5):662-71. doi: 10.1016/j.ejca.2011.08.012. Epub 2011 Sep 22. Eur J Cancer. 2012. PMID: 21945100
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