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Page 1
Flexible and cost-effective genomic surveillance of P. falciparum malaria with targeted nanopore sequencing.
de Cesare M, Mwenda M, Jeffreys AE, Chirwa J, Drakeley C, Schneider K, Mambwe B, Glanz K, Ntalla C, Carrasquilla M, Portugal S, Verity RJ, Bailey JA, Ghinai I, Busby GB, Hamainza B, Hawela M, Bridges DJ, Hendry JA. de Cesare M, et al. Among authors: busby gb. Nat Commun. 2024 Feb 15;15(1):1413. doi: 10.1038/s41467-024-45688-z. Nat Commun. 2024. PMID: 38360754 Free PMC article.
Polygenic Risk Score (PRS) Combined with NGS Panel Testing Increases Accuracy in Hereditary Breast Cancer Risk Estimation.
Tsoulos N, Papadopoulou E, Agiannitopoulos K, Grigoriadis D, Tsaousis GN, Bouzarelou D, Gogas H, Troupis T, Venizelos V, Fountzilas E, Theochari M, Ziogas DC, Giassas S, Koumarianou A, Christopoulou A, Busby G, Nasioulas G, Markopoulos C. Tsoulos N, et al. Diagnostics (Basel). 2024 Aug 21;14(16):1826. doi: 10.3390/diagnostics14161826. Diagnostics (Basel). 2024. PMID: 39202314 Free PMC article.
Polygenic Risk Scores: Genomes to Risk Prediction.
Hayeck TJ, Busby GB, Chun S, Lewis ACF, Roberts MC, Vilhjálmsson BJ. Hayeck TJ, et al. Among authors: busby gb. Clin Chem. 2023 May 26:hvad049. doi: 10.1093/clinchem/hvad049. Online ahead of print. Clin Chem. 2023. PMID: 37232050 Free PMC article. No abstract available.
An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples.
MalariaGEN; Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, Amenga-Etego L, Andagalu B, Anderson TJC, Andrianaranjaka V, Apinjoh T, Ariani C, Ashley EA, Auburn S, Awandare GA, Ba H, Baraka V, Barry AE, Bejon P, Bertin GI, Boni MF, Borrmann S, Bousema T, Branch O, Bull PC, Busby GBJ, Chookajorn T, Chotivanich K, Claessens A, Conway D, Craig A, D'Alessandro U, Dama S, Day NP, Denis B, Diakite M, Djimdé A, Dolecek C, Dondorp AM, Drakeley C, Drury E, Duffy P, Echeverry DF, Egwang TG, Erko B, Fairhurst RM, Faiz A, Fanello CA, Fukuda MM, Gamboa D, Ghansah A, Golassa L, Goncalves S, Hamilton WL, Harrison GLA, Hart L, Henrichs C, Hien TT, Hill CA, Hodgson A, Hubbart C, Imwong M, Ishengoma DS, Jackson SA, Jacob CG, Jeffery B, Jeffreys AE, Johnson KJ, Jyothi D, Kamaliddin C, Kamau E, Kekre M, Kluczynski K, Kochakarn T, Konaté A, Kwiatkowski DP, Kyaw MP, Lim P, Lon C, Loua KM, Maïga-Ascofaré O, Malangone C, Manske M, Marfurt J, Marsh K, Mayxay M, Miles A, Miotto O, Mobegi V, Mokuolu OA, Montgomery J, Mueller I, Newton PN, Nguyen T, Nguyen TN, Noedl H, Nosten F, Noviyanti R, Nzila A, Ochola-Oyier LI, Ocholla H, Oduro A, Omedo I, Onyamboko MA, Ouedraogo JB, Oy… See abstract for full author list ➔ MalariaGEN, et al. Among authors: busby gbj. Wellcome Open Res. 2021 Jul 13;6:42. doi: 10.12688/wellcomeopenres.16168.2. eCollection 2021. Wellcome Open Res. 2021. PMID: 33824913 Free PMC article.
Admixture into and within sub-Saharan Africa.
Busby GB, Band G, Si Le Q, Jallow M, Bougama E, Mangano VD, Amenga-Etego LN, Enimil A, Apinjoh T, Ndila CM, Manjurano A, Nyirongo V, Doumba O, Rockett KA, Kwiatkowski DP, Spencer CC; Malaria Genomic Epidemiology Network. Busby GB, et al. Elife. 2016 Jun 21;5:e15266. doi: 10.7554/eLife.15266. Elife. 2016. PMID: 27324836 Free PMC article.
Resistance to malaria through structural variation of red blood cell invasion receptors.
Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP; Malaria Genomic Epidemiology Network. Leffler EM, et al. Science. 2017 Jun 16;356(6343):eaam6393. doi: 10.1126/science.aam6393. Epub 2017 May 18. Science. 2017. PMID: 28522690 Free PMC article.
Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑α 3.7I form of α-thalassaemia using genome-wide microarray data.
Ndila CM, Nyirongo V, Macharia AW, Jeffreys AE, Rowlands K, Hubbart C, Busby GBJ, Band G, Harding RM, Rockett KA, Williams TN; MalariaGEN Consortium. Ndila CM, et al. Among authors: busby gbj. Wellcome Open Res. 2021 Sep 22;5:287. doi: 10.12688/wellcomeopenres.16320.2. eCollection 2020. Wellcome Open Res. 2021. PMID: 34632085 Free PMC article.
27 results