Kubo S - Search Results

1

Preclinical Characterization of ASP2713, a Novel Igβ and FcγRIIB Cross-Linking Antibody, for Prediction of Human Pharmacokinetics and Clinically Effective Dose.

Konishi K, Nakamura K, Hanada Y, Kitanaga Y, Kubo S, Kinugasa F, Yamajuku D, Maeda M, Yamamoto N, Minematsu T, Ohbuchi M, Kondo Y, Sumida T. Konishi K, et al. Among authors: kubo s. J Pharm Sci. 2022 Sep;111(9):2630-2638. doi: 10.1016/j.xphs.2022.06.006. Epub 2022 Jun 11. J Pharm Sci. 2022. PMID: 35700799

2

Generation and characterization of a potent fully human monoclonal antibody against the interleukin-23 receptor.

Sasaki-Iwaoka H, Ohori M, Imasato A, Taguchi K, Minoura K, Saito T, Kushima K, Imamura E, Kubo S, Furukawa S, Morokata T. Sasaki-Iwaoka H, et al. Among authors: kubo s. Eur J Pharmacol. 2018 Jun 5;828:89-96. doi: 10.1016/j.ejphar.2018.03.036. Epub 2018 Mar 26. Eur J Pharmacol. 2018. PMID: 29588152

3

Expansion of T follicular helper-T helper 1 like cells through epigenetic regulation by signal transducer and activator of transcription factors.

Ma X, Nakayamada S, Kubo S, Sakata K, Yamagata K, Miyazaki Y, Yoshikawa M, Kitanaga Y, Zhang M, Tanaka Y. Ma X, et al. Among authors: kubo s. Ann Rheum Dis. 2018 Sep;77(9):1354-1361. doi: 10.1136/annrheumdis-2017-212652. Epub 2018 May 31. Ann Rheum Dis. 2018. PMID: 29853448

4

Optimization and in vivo evaluation of pyrazolopyridines as a potent and selective PI3Kδ inhibitor.

Hamajima T, Takahashi F, Kato K, Sugano Y, Yamaki S, Moritomo A, Kubo S, Nakamura K, Yamagami K, Hamakawa N, Yokoo K, Fukahori H. Hamajima T, et al. Among authors: kubo s. Bioorg Med Chem. 2018 Aug 7;26(14):3917-3924. doi: 10.1016/j.bmc.2018.06.012. Epub 2018 Jun 15. Bioorg Med Chem. 2018. PMID: 29907471

5

Janus Kinase Inhibitor Baricitinib Modulates Human Innate and Adaptive Immune System.

Kubo S, Nakayamada S, Sakata K, Kitanaga Y, Ma X, Lee S, Ishii A, Yamagata K, Nakano K, Tanaka Y. Kubo S, et al. Front Immunol. 2018 Jun 28;9:1510. doi: 10.3389/fimmu.2018.01510. eCollection 2018. Front Immunol. 2018. PMID: 30002661 Free PMC article.

6

AS2762900-00, a potent anti-human IL-23 receptor monoclonal antibody, prevents epidermal hyperplasia in a psoriatic human skin xenograft model.

Sasaki-Iwaoka H, Taguchi K, Okada Y, Imamura E, Kubo S, Furukawa S, Morokata T. Sasaki-Iwaoka H, et al. Among authors: kubo s. Eur J Pharmacol. 2019 Jan 15;843:190-198. doi: 10.1016/j.ejphar.2018.11.030. Epub 2018 Nov 22. Eur J Pharmacol. 2019. PMID: 30472202

7

Type I and II interferons commit to abnormal expression of chemokine receptor on B cells in patients with systemic lupus erythematosus.

Yoshikawa M, Nakayamada S, Kubo S, Nawata A, Kitanaga Y, Iwata S, Sakata K, Ma X, Wang SP, Nakano K, Saito K, Tanaka Y. Yoshikawa M, et al. Among authors: kubo s. Clin Immunol. 2019 Mar;200:1-9. doi: 10.1016/j.clim.2018.12.017. Epub 2018 Dec 19. Clin Immunol. 2019. PMID: 30576845

8

Optimization of 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidines to generate a highly selective PI3Kδ inhibitor.

Hamajima T, Takahashi F, Kato K, Sugano Y, Yamaki S, Suzuki D, Moritomo A, Kubo S, Nakamura K, Yamagami K, Yokoo K, Fukahori H. Hamajima T, et al. Among authors: kubo s. Bioorg Med Chem. 2019 Mar 15;27(6):1056-1064. doi: 10.1016/j.bmc.2019.02.001. Epub 2019 Feb 1. Bioorg Med Chem. 2019. PMID: 30755348

9

In vitro pharmacological effects of peficitinib on lymphocyte activation: a potential treatment for systemic sclerosis with JAK inhibitors.

Kitanaga Y, Imamura E, Nakahara Y, Fukahori H, Fujii Y, Kubo S, Nakayamada S, Tanaka Y. Kitanaga Y, et al. Among authors: kubo s. Rheumatology (Oxford). 2020 Aug 1;59(8):1957-1968. doi: 10.1093/rheumatology/kez526. Rheumatology (Oxford). 2020. PMID: 31764973 Free PMC article.

10

Discovery of a novel Igβ and FcγRIIB cross-linking antibody, ASP2713, and its potential application in the treatment of systemic lupus erythematosus.

Kitanaga Y, Yamajuku D, Kubo S, Nakamura K, Maeda M, Seki M, Kaneko Y, Kinugasa F, Morokata T, Kondo Y, Yoshinari H, Nakayamada S, Sumida T, Tanaka Y. Kitanaga Y, et al. Among authors: kubo s. Int Immunopharmacol. 2021 Dec;101(Pt B):108343. doi: 10.1016/j.intimp.2021.108343. Epub 2021 Nov 12. Int Immunopharmacol. 2021. PMID: 34781122

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