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Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure.
Li Z, Xia H, Sharp TE 3rd, LaPenna KB, Elrod JW, Casin KM, Liu K, Calvert JW, Chau VQ, Salloum FN, Xu S, Xian M, Nagahara N, Goodchild TT, Lefer DJ. Li Z, et al. Among authors: xia h. Circ Res. 2022 Jul 22;131(3):222-235. doi: 10.1161/CIRCRESAHA.121.319817. Epub 2022 Jun 14. Circ Res. 2022. PMID: 35701874 Free PMC article.
Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation.
Feng Y, Yue X, Xia H, Bindom SM, Hickman PJ, Filipeanu CM, Wu G, Lazartigues E. Feng Y, et al. Among authors: xia h. Circ Res. 2008 Mar 28;102(6):729-36. doi: 10.1161/CIRCRESAHA.107.169110. Epub 2008 Feb 7. Circ Res. 2008. PMID: 18258853 Free PMC article.
Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure.
Li Z, Xia H, Sharp TE 3rd, LaPenna KB, Katsouda A, Elrod JW, Pfeilschifter J, Beck KF, Xu S, Xian M, Goodchild TT, Papapetropoulos A, Lefer DJ. Li Z, et al. Among authors: xia h. Circ Res. 2023 Jan 20;132(2):154-166. doi: 10.1161/CIRCRESAHA.122.321326. Epub 2022 Dec 28. Circ Res. 2023. PMID: 36575984 Free PMC article.
Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a "2-Hit" Murine Model.
LaPenna KB, Li Z, Doiron JE, Sharp TE 3rd, Xia H, Moles K, Koul K, Wang JS, Polhemus DJ, Goodchild TT, Patel RB, Shah SJ, Lefer DJ. LaPenna KB, et al. Among authors: xia h. J Am Heart Assoc. 2023 Feb 21;12(4):e028480. doi: 10.1161/JAHA.122.028480. Epub 2023 Feb 8. J Am Heart Assoc. 2023. PMID: 36752224 Free PMC article.
Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.
Doiron JE, Xia H, Yu X, Nevins AR, LaPenna KB, Sharp TE 3rd, Goodchild TT, Allerton TD, Elgazzaz M, Lazartigues E, Shah SJ, Li Z, Lefer DJ. Doiron JE, et al. Among authors: xia h. Br J Pharmacol. 2024 Nov;181(21):4294-4310. doi: 10.1111/bph.16493. Epub 2024 Jul 9. Br J Pharmacol. 2024. PMID: 38982742
5,914 results