Datta D - Search Results

1

Aminooxy Click Chemistry as a Tool for Bis-homo and Bis-hetero Ligand Conjugation to Nucleic Acids.

Datta D, Mori S, Madaoui M, Wassarman K, Zlatev I, Manoharan M. Datta D, et al. Org Lett. 2022 Jul 1;24(25):4496-4501. doi: 10.1021/acs.orglett.2c00988. Epub 2022 Jun 17. Org Lett. 2022. PMID: 35715221 Free PMC article.

2

A Chemical Approach to Introduce 2,6-Diaminopurine and 2-Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups.

Madaoui M, Datta D, Wassarman K, Zlatev I, Egli M, Ross BS, Manoharan M. Madaoui M, et al. Among authors: datta d. Org Lett. 2022 Aug 26;24(33):6111-6116. doi: 10.1021/acs.orglett.2c01848. Epub 2022 Aug 16. Org Lett. 2022. PMID: 35973215 Free PMC article.

3

Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex.

Datta D, Theile CS, Wassarman K, Qin J, Racie T, Schmidt K, Jiang Y, Sigel R, Janas MM, Egli M, Manoharan M. Datta D, et al. Chem Commun (Camb). 2023 May 23;59(42):6347-6350. doi: 10.1039/d3cc01143g. Chem Commun (Camb). 2023. PMID: 37144553

4

Conformation matters: siRNAs with antisense strands with 5'-(E)-vinyl-phosphonate-α-L-LNA elicit stronger RNAi-mediated gene silencing than those with 5'-(E)-vinyl-phosphonate-LNA.

Datta D, Kumar P, Mandal S, Krampert M, Egli M, Hrdlicka PJ, Manoharan M. Datta D, et al. Chem Commun (Camb). 2024 Nov 5;60(89):13024-13027. doi: 10.1039/d4cc04302b. Chem Commun (Camb). 2024. PMID: 39431399

5

Structural Design and Synthesis of Bimodal PNA That Simultaneously Binds Two Complementary DNAs To Form Fused Double Duplexes.

Gupta MK, Madhanagopal BR, Datta D, Ganesh KN. Gupta MK, et al. Among authors: datta d. Org Lett. 2020 Jul 2;22(13):5255-5260. doi: 10.1021/acs.orglett.0c01950. Epub 2020 Jun 18. Org Lett. 2020. PMID: 32551691

6

Sulfonic nucleic acids (SNAs): a new class of substrate mimics for ribonuclease A inhibition.

Datta D, Dasgupta S, Pathak T. Datta D, et al. Org Biomol Chem. 2019 Aug 14;17(30):7215-7221. doi: 10.1039/c9ob01250h. Epub 2019 Jul 19. Org Biomol Chem. 2019. PMID: 31322157

7

New archetypes in self-assembled Phe-Phe motif induced nanostructures from nucleoside conjugated-diphenylalanines.

Datta D , Tiwari O , Ganesh KN . Datta D , et al. Nanoscale. 2018 Feb 15;10(7):3212-3224. doi: 10.1039/c7nr08436f. Nanoscale. 2018. PMID: 29379926

8

Self-Assembly of Diphenylalanine-Peptide Nucleic Acid Conjugates.

Datta D, Tiwari O, Gupta MK. Datta D, et al. ACS Omega. 2019 Jun 20;4(6):10715-10728. doi: 10.1021/acsomega.9b00047. eCollection 2019 Jun 30. ACS Omega. 2019. PMID: 31460170 Free PMC article.

9

A convenient route to synthesize N²-(isobutyryl)-9-(carboxymethyl)guanine for aeg-PNA backbone.

Datta D. Datta D. Nucleosides Nucleotides Nucleic Acids. 2020;39(4):530-541. doi: 10.1080/15257770.2019.1666139. Epub 2019 Oct 7. Nucleosides Nucleotides Nucleic Acids. 2020. PMID: 31588835

10

Gem-dimethyl peptide nucleic acid (α/β/γ-gdm-PNA) monomers: synthesis and the role of gdm-substituents in preferential stabilisation of Z/E-rotamers.

Kulkarni P, Datta D, Ramabhadran RO, Ganesh K. Kulkarni P, et al. Among authors: datta d. Org Biomol Chem. 2021 Jul 28;19(29):6534-6545. doi: 10.1039/d1ob01097b. Org Biomol Chem. 2021. PMID: 34259296

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