Song Z - Search Results

1

Synthesis and evaluation of imidazo[1,2-a]pyrazine derivatives as small molecule Gαq/11 inhibitors against uveal melanoma.

Deng JJ, Liu L, Ge Y, Song Z, Huang J, Fan G, Xiong XF. Deng JJ, et al. Among authors: song z. Eur J Med Chem. 2022 Sep 5;239:114520. doi: 10.1016/j.ejmech.2022.114520. Epub 2022 Jun 11. Eur J Med Chem. 2022. PMID: 35716516

2

Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

Yu H, Li Y, Ge Y, Song Z, Wang C, Huang S, Jin Y, Han X, Zhen Y, Liu K, Zhou Y, Ma X. Yu H, et al. Among authors: song z. Eur J Med Chem. 2016 Mar 3;110:195-203. doi: 10.1016/j.ejmech.2016.01.045. Epub 2016 Jan 26. Eur J Med Chem. 2016. PMID: 26829280

3

Challenges and Perspectives on the Development of Small-Molecule EGFR Inhibitors against T790M-Mediated Resistance in Non-Small-Cell Lung Cancer.

Song Z, Ge Y, Wang C, Huang S, Shu X, Liu K, Zhou Y, Ma X. Song Z, et al. J Med Chem. 2016 Jul 28;59(14):6580-94. doi: 10.1021/acs.jmedchem.5b00840. Epub 2016 Feb 26. J Med Chem. 2016. PMID: 26882288

4

Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

Song Z, Jin Y, Ge Y, Wang C, Zhang J, Tang Z, Peng J, Liu K, Li Y, Ma X. Song Z, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5505-5512. doi: 10.1016/j.bmc.2016.09.001. Epub 2016 Sep 3. Bioorg Med Chem. 2016. PMID: 27634676

5

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

Song Z, Huang S, Yu H, Jiang Y, Wang C, Meng Q, Shu X, Sun H, Liu K, Li Y, Ma X. Song Z, et al. Eur J Med Chem. 2017 Jun 16;133:329-339. doi: 10.1016/j.ejmech.2017.03.083. Epub 2017 Apr 2. Eur J Med Chem. 2017. PMID: 28395219

6

Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies.

Song Z, Wang M, Ge Y, Chen XP, Xu Z, Sun Y, Xiong XF. Song Z, et al. Acta Pharm Sin B. 2021 Jan;11(1):13-29. doi: 10.1016/j.apsb.2020.07.010. Epub 2020 Jul 26. Acta Pharm Sin B. 2021. PMID: 33532178 Free PMC article. Review.

7

Design, Synthesis, and Evaluation of Small Molecule Gαq/11 Protein Inhibitors for the Treatment of Uveal Melanoma.

Ge Y, Shi S, Deng JJ, Chen XP, Song Z, Liu L, Lou L, Zhang X, Xiong XF. Ge Y, et al. Among authors: song z. J Med Chem. 2021 Mar 25;64(6):3131-3152. doi: 10.1021/acs.jmedchem.0c01977. Epub 2021 Mar 15. J Med Chem. 2021. PMID: 33715360

8

Silanol: a bifunctional group for peptide synthesis and late-stage functionalization.

Hu QL, Hou KQ, Li J, Ge Y, Song ZD, Chan ASC, Xiong XF. Hu QL, et al. Chem Sci. 2020 Jun 3;11(23):6070-6074. doi: 10.1039/d0sc02439b. Chem Sci. 2020. PMID: 34094099 Free PMC article.

9

Cleavable and tunable cysteine-specific arylation modification with aryl thioethers.

Li J, Deng JJ, Yin Z, Hu QL, Ge Y, Song Z, Zhang Y, Chan ASC, Li H, Xiong XF. Li J, et al. Among authors: song z. Chem Sci. 2021 Feb 18;12(14):5209-5215. doi: 10.1039/d0sc06576e. Chem Sci. 2021. PMID: 34168774 Free PMC article.

10

Targeting mutated GTPase KRAS in tumor therapies.

Fan G, Lou L, Song Z, Zhang X, Xiong XF. Fan G, et al. Among authors: song z. Eur J Med Chem. 2021 Dec 15;226:113816. doi: 10.1016/j.ejmech.2021.113816. Epub 2021 Sep 4. Eur J Med Chem. 2021. PMID: 34520956 Review.

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