Gerak CA - Search Results

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A biosensor of protein foldedness identifies increased "holdase" activity of chaperones in the nucleus following increased cytosolic protein aggregation.

Raeburn CB, Ormsby AR, Cox D, Gerak CA, Makhoul C, Moily NS, Ebbinghaus S, Dickson A, McColl G, Hatters DM. Raeburn CB, et al. Among authors: gerak ca. J Biol Chem. 2022 Aug;298(8):102158. doi: 10.1016/j.jbc.2022.102158. Epub 2022 Jun 17. J Biol Chem. 2022. PMID: 35724963 Free PMC article.

Biophysical characterization of the ETV6 PNT domain polymerization interfaces.

Gerak CAN, Cho SY, Kolesnikov M, Okon M, Murphy MEP, Sessions RB, Roberge M, McIntosh LP. Gerak CAN, et al. J Biol Chem. 2021 Jan-Jun;296:100284. doi: 10.1016/j.jbc.2021.100284. Epub 2021 Jan 13. J Biol Chem. 2021. PMID: 33450226 Free PMC article.

A Multipronged Screening Approach Targeting Inhibition of ETV6 PNT Domain Polymerization.

Gerak CAN, Zhang SM, Balgi AD, Sadowski IJ, Sessions RB, McIntosh LP, Roberge M. Gerak CAN, et al. SLAS Discov. 2021 Jun;26(5):698-711. doi: 10.1177/2472555220979599. Epub 2020 Dec 21. SLAS Discov. 2021. PMID: 33345679 Free article.

The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418.

Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M. Ferguson MW, et al. Among authors: gerak can. PLoS One. 2019 May 23;14(5):e0216423. doi: 10.1371/journal.pone.0216423. eCollection 2019. PLoS One. 2019. PMID: 31120902 Free PMC article.

Both Chemical and Non-Chemical Steps Limit the Catalytic Efficiency of Family 4 Glycoside Hydrolases.

Sannikova N, Gerak CAN, Shidmoossavee FS, King DT, Shamsi Kazem Abadi S, Lewis AR, Bennet AJ. Sannikova N, et al. Among authors: gerak can. Biochemistry. 2018 Jun 19;57(24):3378-3386. doi: 10.1021/acs.biochem.8b00117. Epub 2018 Apr 20. Biochemistry. 2018. PMID: 29630821

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