DeFea KA - Search Results

1

β-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation.

Schiff HV, Rivas CM, Pederson WP, Sandoval E, Gillman S, Prisco J, Kume M, Dussor G, Vagner J, Ledford JG, Price TJ, DeFea KA, Boitano S. Schiff HV, et al. Among authors: defea ka. Br J Pharmacol. 2023 Mar;180(5):667-680. doi: 10.1111/bph.15903. Epub 2022 Dec 5. Br J Pharmacol. 2023. PMID: 35735078 Free PMC article.

2

β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway.

Nichols HL, Saffeddine M, Theriot BS, Hegde A, Polley D, El-Mays T, Vliagoftis H, Hollenberg MD, Wilson EH, Walker JK, DeFea KA. Nichols HL, et al. Among authors: defea ka. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16660-5. doi: 10.1073/pnas.1208881109. Epub 2012 Sep 25. Proc Natl Acad Sci U S A. 2012. PMID: 23012429 Free PMC article.

3

The novel PAR2 ligand C391 blocks multiple PAR2 signalling pathways in vitro and in vivo.

Boitano S, Hoffman J, Flynn AN, Asiedu MN, Tillu DV, Zhang Z, Sherwood CL, Rivas CM, DeFea KA, Vagner J, Price TJ. Boitano S, et al. Among authors: defea ka. Br J Pharmacol. 2015 Sep;172(18):4535-4545. doi: 10.1111/bph.13238. Epub 2015 Aug 3. Br J Pharmacol. 2015. PMID: 26140338 Free PMC article.

4

Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.

Yee MC, Nichols HL, Polley D, Saifeddine M, Pal K, Lee K, Wilson EH, Daines MO, Hollenberg MD, Boitano S, DeFea KA. Yee MC, et al. Among authors: defea ka. Am J Physiol Lung Cell Mol Physiol. 2018 Dec 1;315(6):L1042-L1057. doi: 10.1152/ajplung.00196.2018. Epub 2018 Oct 18. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 30335499 Free PMC article.

5

Proteinase-activated receptor-2 antagonist C391 inhibits Alternaria-induced airway epithelial signalling and asthma indicators in acute exposure mouse models.

Rivas CM, Yee MC, Addison KJ, Lovett M, Pal K, Ledford JG, Dussor G, Price TJ, Vagner J, DeFea KA, Boitano S. Rivas CM, et al. Among authors: defea ka. Br J Pharmacol. 2022 May;179(10):2208-2222. doi: 10.1111/bph.15745. Epub 2022 Feb 1. Br J Pharmacol. 2022. PMID: 34841515 Free article.

6

Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression.

Rivas CM, Schiff HV, Moutal A, Khanna R, Kiela PR, Dussor G, Price TJ, Vagner J, DeFea KA, Boitano S. Rivas CM, et al. Among authors: defea ka. Biochem Biophys Res Commun. 2022 Feb 5;591:13-19. doi: 10.1016/j.bbrc.2021.12.090. Epub 2021 Dec 29. Biochem Biophys Res Commun. 2022. PMID: 34990903 Free PMC article.

7

Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2.

Wang P, Jiang Y, Wang Y, Shyy JY, DeFea KA. Wang P, et al. Among authors: defea ka. BMC Biochem. 2010 Sep 21;11:36. doi: 10.1186/1471-2091-11-36. BMC Biochem. 2010. PMID: 20858278 Free PMC article.

8

β-arrestin-dependent actin reorganization: bringing the right players together at the leading edge.

Min J, Defea K. Min J, et al. Mol Pharmacol. 2011 Nov;80(5):760-8. doi: 10.1124/mol.111.072470. Epub 2011 Aug 11. Mol Pharmacol. 2011. PMID: 21836019 Review.

9

Molecular mechanisms underlying beta-arrestin-dependent chemotaxis and actin-cytoskeletal reorganization.

McGovern KW, DeFea KA. McGovern KW, et al. Among authors: defea ka. Handb Exp Pharmacol. 2014;219:341-59. doi: 10.1007/978-3-642-41199-1_17. Handb Exp Pharmacol. 2014. PMID: 24292838

10

Functional inhibition of PAR2 alleviates allergen-induced airway hyperresponsiveness and inflammation.

Asaduzzaman M, Nadeem A, Arizmendi N, Davidson C, Nichols HL, Abel M, Ionescu LI, Puttagunta L, Thebaud B, Gordon J, DeFea K, Hollenberg MD, Vliagoftis H. Asaduzzaman M, et al. Clin Exp Allergy. 2015 Dec;45(12):1844-55. doi: 10.1111/cea.12628. Clin Exp Allergy. 2015. PMID: 26312432

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

51 results

Search Page

Filters