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Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors.
Makino Y, Oe C, Iwama K, Suzuki S, Nishiyama A, Hasegawa K, Okuda H, Hirata K, Ueno M, Kawaji K, Sasano M, Usui E, Hosaka T, Yabuki Y, Shirouzu M, Katsumi M, Murayama K, Hayashi H, Kodama EN. Makino Y, et al. Among authors: nishiyama a. Commun Biol. 2022 Jun 23;5(1):619. doi: 10.1038/s42003-022-03555-x. Commun Biol. 2022. PMID: 35739195 Free PMC article.
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: nishiyama a. Nat Commun. 2023 Feb 25;14(1):1076. doi: 10.1038/s41467-023-36729-0. Nat Commun. 2023. PMID: 36841831 Free PMC article.
Helix-based screening with structure prediction using artificial intelligence has potential for the rapid development of peptide inhibitors targeting class I viral fusion.
Suzuki S, Kuroda M, Aoki K, Kawaji K, Hiramatsu Y, Sasano M, Nishiyama A, Murayama K, Kodama EN, Oishi S, Hayashi H. Suzuki S, et al. Among authors: nishiyama a. RSC Chem Biol. 2023 Nov 7;5(2):131-140. doi: 10.1039/d3cb00166k. eCollection 2024 Feb 7. RSC Chem Biol. 2023. PMID: 38333196 Free PMC article.
HIF1α Plays a Crucial Role in the Development of TFE3-Rearranged Renal Cell Carcinoma by Orchestrating a Metabolic Shift Toward Fatty Acid Synthesis.
Nishizawa H, Funasaki S, Ma W, Kubota Y, Watanabe K, Arima Y, Kuroda S, Ito T, Furuya M, Motoshima T, Nishiyama A, Mehanna S, Satou Y, Hasumi H, Jikuya R, Makiyama K, Tamura T, Oike Y, Tanaka Y, Suda T, Schmidt LS, Linehan WM, Baba M, Kamba T. Nishizawa H, et al. Among authors: nishiyama a. Genes Cells. 2025 Jan;30(1):e13195. doi: 10.1111/gtc.13195. Genes Cells. 2025. PMID: 39807625 Free PMC article.
EGFR-V834L combined with L858R mutation reduced afatinib sensitivity and associated to early recurrence in lung cancer.
Terada N, Koba H, Nanjo S, Kimura H, Nishiyama A, Yoneda T, Takeda T, Shirasaki H, Nishi K, Sone T, Yamada T, Takayama K, Shibata K, Matsuoka H, Kita T, Nagata K, Tambo Y, Ohkura N, Hara J, Kasahara K, Kohsaka S, Mano H, Yano S. Terada N, et al. Among authors: nishiyama a. Transl Lung Cancer Res. 2024 Nov 30;13(11):3067-3082. doi: 10.21037/tlcr-24-471. Epub 2024 Nov 28. Transl Lung Cancer Res. 2024. PMID: 39670006 Free PMC article.
Digital hypertension, implementation hypertension, and internationalization - 3 pillars of Japanese Society of Hypertension 2024-2026 advancing hypertension science from Japan to the world in the information network era.
Kario K, Nishiyama A, Shibata S, Arima H, Furuhashi M, Ichihara A, Ishida M, Katsuya T, Kishi T, Miura K, Miura SI, Mogi M, Ohishi M, Shibata H, Shimosawa T, Sugawara A, Tamura K, Toyoda K, Yamamoto K, Node K. Kario K, et al. Among authors: nishiyama a. Hypertens Res. 2025 Jan;48(1):1-5. doi: 10.1038/s41440-024-02045-3. Epub 2024 Dec 6. Hypertens Res. 2025. PMID: 39643706 No abstract available.
1,259 results