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Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease.
Assante G, Chandrasekaran S, Ng S, Tourna A, Chung CH, Isse KA, Banks JL, Soffientini U, Filippi C, Dhawan A, Liu M, Rozen SG, Hoare M, Campbell P, Ballard JWO, Turner N, Morris MJ, Chokshi S, Youngson NA. Assante G, et al. Among authors: turner n. Genome Med. 2022 Jun 23;14(1):67. doi: 10.1186/s13073-022-01071-5. Genome Med. 2022. PMID: 35739588 Free PMC article.
SIRT2 transgenic over-expression does not impact lifespan in mice.
Wu LE, Fiveash CE, Bentley NL, Kang MJ, Govindaraju H, Barbour JA, Wilkins BP, Hancock SE, Madawala R, Das A, Massudi H, Li C, Kim LJ, Wong ASA, Marinova MB, Sultani G, Das A, Youngson NA, Le Couteur DG, Sinclair DA, Turner N. Wu LE, et al. Among authors: turner n. Aging Cell. 2023 Dec;22(12):e14027. doi: 10.1111/acel.14027. Epub 2023 Nov 27. Aging Cell. 2023. PMID: 38009412 Free PMC article.
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice.
Solon-Biet SM, McMahon AC, Ballard JW, Ruohonen K, Wu LE, Cogger VC, Warren A, Huang X, Pichaud N, Melvin RG, Gokarn R, Khalil M, Turner N, Cooney GJ, Sinclair DA, Raubenheimer D, Le Couteur DG, Simpson SJ. Solon-Biet SM, et al. Among authors: turner n. Cell Metab. 2014 Mar 4;19(3):418-30. doi: 10.1016/j.cmet.2014.02.009. Cell Metab. 2014. PMID: 24606899 Free PMC article.
The Influence of Macronutrients on Splanchnic and Hepatic Lymphocytes in Aging Mice.
Le Couteur DG, Tay SS, Solon-Biet S, Bertolino P, McMahon AC, Cogger VC, Colakoglu F, Warren A, Holmes AJ, Pichaud N, Horan M, Correa C, Melvin RG, Turner N, Ballard JW, Ruohonen K, Raubenheimer D, Simpson SJ. Le Couteur DG, et al. Among authors: turner n. J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1499-507. doi: 10.1093/gerona/glu196. Epub 2014 Oct 21. J Gerontol A Biol Sci Med Sci. 2015. PMID: 25335766
NAD+ Repletion Rescues Female Fertility during Reproductive Aging.
Bertoldo MJ, Listijono DR, Ho WJ, Riepsamen AH, Goss DM, Richani D, Jin XL, Mahbub S, Campbell JM, Habibalahi A, Loh WN, Youngson NA, Maniam J, Wong ASA, Selesniemi K, Bustamante S, Li C, Zhao Y, Marinova MB, Kim LJ, Lau L, Wu RM, Mikolaizak AS, Araki T, Le Couteur DG, Turner N, Morris MJ, Walters KA, Goldys E, O'Neill C, Gilchrist RB, Sinclair DA, Homer HA, Wu LE. Bertoldo MJ, et al. Among authors: turner n. Cell Rep. 2020 Feb 11;30(6):1670-1681.e7. doi: 10.1016/j.celrep.2020.01.058. Cell Rep. 2020. PMID: 32049001 Free PMC article.
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle.
Diaz-Vegas A, Madsen S, Cooke KC, Carroll L, Khor JXY, Turner N, Lim XY, Astore MA, Morris JC, Don AS, Garfield A, Zarini S, Zemski Berry KA, Ryan AP, Bergman BC, Brozinick JT, James DE, Burchfield JG. Diaz-Vegas A, et al. Among authors: turner n. Elife. 2023 Dec 27;12:RP87340. doi: 10.7554/eLife.87340. Elife. 2023. PMID: 38149844 Free PMC article.
1,940 results