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STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion.
Li J, Williams MJ, Park HJ, Bastos HP, Wang X, Prins D, Wilson NK, Johnson C, Sham K, Wantoch M, Watcham S, Kinston SJ, Pask DC, Hamilton TL, Sneade R, Waller AK, Ghevaert C, Vassiliou GS, Laurenti E, Kent DG, Göttgens B, Green AR. Li J, et al. Among authors: park hj. Blood. 2022 Oct 6;140(14):1592-1606. doi: 10.1182/blood.2021014009. Blood. 2022. PMID: 35767701 Free PMC article.
Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage.
Li J, Prins D, Park HJ, Grinfeld J, Gonzalez-Arias C, Loughran S, Dovey OM, Klampfl T, Bennett C, Hamilton TL, Pask DC, Sneade R, Williams M, Aungier J, Ghevaert C, Vassiliou GS, Kent DG, Green AR. Li J, et al. Among authors: park hj. Blood. 2018 Feb 8;131(6):649-661. doi: 10.1182/blood-2017-09-806356. Epub 2017 Dec 27. Blood. 2018. PMID: 29282219 Free article.
Maintenance of hematopoietic stem cells by tyrosine-unphosphorylated STAT5 and JAK inhibition.
Williams MJ, Wang X, Bastos HP, Grondys-Kotarba G, Wu Q, Jin S, Johnson CS, Mende N, Calderbank EF, Wantoch M, Park HJ, Mantica G, Hannah RL, Wilson NK, Pask DC, Hamilton TL, Kinston SJ, Asby R, Sneade R, Baxter EJ, Campbell PJ, Vassiliou GS, Laurenti E PhD, Li J, Gottgens B, Green AR. Williams MJ, et al. Among authors: park hj. Blood Adv. 2024 Oct 7:bloodadvances.2024014046. doi: 10.1182/bloodadvances.2024014046. Online ahead of print. Blood Adv. 2024. PMID: 39374575 Free PMC article.
A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion.
Flury A, Aljayousi L, Park HJ, Khakpour M, Mechler J, Aziz S, McGrath JD, Deme P, Sandberg C, González Ibáñez F, Braniff O, Ngo T, Smith S, Velez M, Ramirez DM, Avnon-Klein D, Murray JW, Liu J, Parent M, Mingote S, Haughey NJ, Werneburg S, Tremblay MÈ, Ayata P. Flury A, et al. Among authors: park hj. Neuron. 2024 Dec 19:S0896-6273(24)00875-4. doi: 10.1016/j.neuron.2024.11.018. Online ahead of print. Neuron. 2024. PMID: 39719704
Accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis.
Park J, Choi W, Seong DY, Jeong S, Lee JY, Park HJ, Chung DS, Yi K, Kim U, Yoon GY, Kim H, Kim T, Ko S, Min EJ, Cho HS, Cho NH, Hong D. Park J, et al. Among authors: park hj. Elife. 2024 Dec 24;13:RP99833. doi: 10.7554/eLife.99833. Elife. 2024. PMID: 39717902 Free PMC article.
6,356 results