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Page 1
STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion.
Li J, Williams MJ, Park HJ, Bastos HP, Wang X, Prins D, Wilson NK, Johnson C, Sham K, Wantoch M, Watcham S, Kinston SJ, Pask DC, Hamilton TL, Sneade R, Waller AK, Ghevaert C, Vassiliou GS, Laurenti E, Kent DG, Göttgens B, Green AR. Li J, et al. Among authors: waller ak. Blood. 2022 Oct 6;140(14):1592-1606. doi: 10.1182/blood.2021014009. Blood. 2022. PMID: 35767701 Free PMC article.
Structurally graduated collagen scaffolds applied to the ex vivo generation of platelets from human pluripotent stem cell-derived megakaryocytes: Enhancing production and purity.
Shepherd JH, Howard D, Waller AK, Foster HR, Mueller A, Moreau T, Evans AL, Arumugam M, Bouët Chalon G, Vriend E, Davidenko N, Ghevaert C, Best SM, Cameron RE. Shepherd JH, et al. Among authors: waller ak. Biomaterials. 2018 Nov;182:135-144. doi: 10.1016/j.biomaterials.2018.08.019. Epub 2018 Aug 8. Biomaterials. 2018. PMID: 30118981
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.
Ho YH, Del Toro R, Rivera-Torres J, Rak J, Korn C, García-García A, Macías D, González-Gómez C, Del Monte A, Wittner M, Waller AK, Foster HR, López-Otín C, Johnson RS, Nerlov C, Ghevaert C, Vainchenker W, Louache F, Andrés V, Méndez-Ferrer S. Ho YH, et al. Among authors: waller ak. Cell Stem Cell. 2019 Sep 5;25(3):407-418.e6. doi: 10.1016/j.stem.2019.06.007. Epub 2019 Jul 11. Cell Stem Cell. 2019. PMID: 31303548 Free PMC article.
CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Bennett C, Lawrence M, Guerrero JA, Stritt S, Waller AK, Yan Y, Mifsud RW, Ballester-Beltrán J, Baig A, Mueller A, Mayer L, Warland J, Penkett CJ, Akbari P, Moreau T, Evans AL, Mookerjee S, Hoffman GJ, Saeb-Parsy K, Adams DJ, Couzens AL, Bender M, Erber WN, Nieswandt B, Read RJ, Ghevaert C. Bennett C, et al. Among authors: waller ak. Blood. 2022 Apr 7;139(14):2227-2239. doi: 10.1182/blood.2021013113. Blood. 2022. PMID: 35051265 Free PMC article.
Highly efficient platelet generation in lung vasculature reproduced by microfluidics.
Zhao X, Alibhai D, Walsh TG, Tarassova N, Englert M, Birol SZ, Li Y, Williams CM, Neal CR, Burkard P, Cross SJ, Aitken EW, Waller AK, Beltrán JB, Gunning PW, Hardeman EC, Agbani EO, Nieswandt B, Hers I, Ghevaert C, Poole AW. Zhao X, et al. Among authors: waller ak. Nat Commun. 2023 Jul 7;14(1):4026. doi: 10.1038/s41467-023-39598-9. Nat Commun. 2023. PMID: 37419900 Free PMC article.
Circulating platelets modulate oligodendrocyte progenitor cell differentiation during remyelination.
Philp AR, Reyes CR, Mansilla J, Sharma A, Zhao C, Valenzuela-Krugmann C, Rawji KS, Gonzalez Martinez GA, Dimas P, Hinrichsen B, Ulloa-Leal C, Waller AK, Bessa de Sousa DM, Castro MA, Aigner L, Ehrenfeld P, Silva ME, Kazanis I, Ghevaert C, Franklin RJM, Rivera FJ. Philp AR, et al. Among authors: waller ak. Elife. 2024 Aug 20;12:RP91757. doi: 10.7554/eLife.91757. Elife. 2024. PMID: 39163103 Free PMC article.
Flow cytometry for near-patient testing in premature neonates reveals variation in platelet function: a novel approach to guide platelet transfusion.
Waller AK, Lantos L, Sammut A, Salgin B, McKinney H, Foster HR, Kriek N, Gibbins JM, Stanworth SJ, Garner SF, Venkatesh V, Curley A, Belteki G, Ghevaert C. Waller AK, et al. Pediatr Res. 2019 May;85(6):874-884. doi: 10.1038/s41390-019-0316-9. Epub 2019 Jan 29. Pediatr Res. 2019. PMID: 30742030 Free PMC article.
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