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Identification of a rapidly-spreading triple mutant for high-level metabolic insecticide resistance in Anopheles gambiae provides a real-time molecular diagnostic for antimalarial intervention deployment.
Njoroge H, Van't Hof A, Oruni A, Pipini D, Nagi SC, Lynd A, Lucas ER, Tomlinson S, Grau-Bove X, McDermott D, Wat'senga FT, Manzambi EZ, Agossa FR, Mokuba A, Irish S, Kabula B, Mbogo C, Bargul J, Paine MJI, Weetman D, Donnelly MJ. Njoroge H, et al. Among authors: oruni a. Mol Ecol. 2022 Aug;31(16):4307-4318. doi: 10.1111/mec.16591. Epub 2022 Jul 12. Mol Ecol. 2022. PMID: 35775282 Free PMC article.
LLIN Evaluation in Uganda Project (LLINEUP): a cross-sectional survey of species diversity and insecticide resistance in 48 districts of Uganda.
Lynd A, Gonahasa S, Staedke SG, Oruni A, Maiteki-Sebuguzi C, Dorsey G, Opigo J, Yeka A, Katureebe A, Kyohere M, Hemingway J, Kamya MR, Donnelly MJ. Lynd A, et al. Among authors: oruni a. Parasit Vectors. 2019 Mar 12;12(1):94. doi: 10.1186/s13071-019-3353-7. Parasit Vectors. 2019. PMID: 30867018 Free PMC article.
LLIN evaluation in Uganda project (LLINEUP): The fabric integrity, chemical content and bioefficacy of long-lasting insecticidal nets treated with and without piperonyl butoxide across two years of operational use in Uganda.
Mechan F, Katureebe A, Tuhaise V, Mugote M, Oruni A, Onyige I, Bumali K, Thornton J, Maxwell K, Kyohere M, Kamya MR, Mutungi P, Kigozi SP, Yeka A, Opigo J, Maiteki-Sebuguzi C, Gonahasa S, Hemingway J, Dorsey G, Reimer LJ, Staedke SG, Donnelly MJ, Lynd A. Mechan F, et al. Among authors: oruni a. Curr Res Parasitol Vector Borne Dis. 2022 May 25;2:100092. doi: 10.1016/j.crpvbd.2022.100092. eCollection 2022. Curr Res Parasitol Vector Borne Dis. 2022. PMID: 35734077 Free PMC article.
Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda.
Kamya MR, Nankabirwa JI, Arinaitwe E, Rek J, Zedi M, Maiteki-Sebuguzi C, Opigo J, Staedke SG, Oruni A, Donnelly MJ, Greenhouse B, Briggs J, Krezanoski PJ, Bousema T, Rosenthal PJ, Olwoch P, Jagannathan P, Rodriguez-Barraquer I, Dorsey G. Kamya MR, et al. Among authors: oruni a. PLOS Glob Public Health. 2024 Aug 29;4(8):e0003254. doi: 10.1371/journal.pgph.0003254. eCollection 2024. PLOS Glob Public Health. 2024. PMID: 39208072 Free PMC article.
LLIN Evaluation in Uganda Project (LLINEUP)-effects of a vector control trial on Plasmodium infection prevalence and genotypic markers of insecticide resistance in Anopheles vectors from 48 districts of Uganda.
Lynd A, Gonahasa S, Staedke SG, Oruni A, Maiteki-Sebuguzi C, Hancock PA, Knight E, Dorsey G, Opigo J, Yeka A, Katureebe A, Kyohere M, Hemingway J, Kamya MR, McDermott D, Lucas ER, Donnelly MJ. Lynd A, et al. Among authors: oruni a. Sci Rep. 2024 Jun 24;14(1):14488. doi: 10.1038/s41598-024-65050-z. Sci Rep. 2024. PMID: 38914669 Free PMC article.
Pyrethroid resistance and gene expression profile of a new resistant An. gambiae colony from Uganda reveals multiple resistance mechanisms and overexpression of Glutathione-S-Transferases linked to survival of PBO-pyrethroid combination.
Oruni A, Lynd A, Njoroge H, Onyige I, Van't Hof AE, Matovu E, Donnelly MJ. Oruni A, et al. Wellcome Open Res. 2024 Apr 29;9:13. doi: 10.12688/wellcomeopenres.19404.2. eCollection 2024. Wellcome Open Res. 2024. PMID: 38813466 Free PMC article.
15 results