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221 results

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Page 1
Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion.
Hussein D, Punjaruk W, Storer LC, Shaw L, Othman R, Peet A, Miller S, Bandopadhyay G, Heath R, Kumari R, Bowman KJ, Braker P, Rahman R, Jones GD, Watson S, Lowe J, Kerr ID, Grundy RG, Coyle B. Hussein D, et al. Among authors: grundy rg. Neuro Oncol. 2011 Jan;13(1):70-83. doi: 10.1093/neuonc/noq144. Epub 2010 Oct 25. Neuro Oncol. 2011. PMID: 20978004 Free PMC article.
Histologically defined central nervous system primitive neuro-ectodermal tumours (CNS-PNETs) display heterogeneous DNA methylation profiles and show relationships to other paediatric brain tumour types.
Schwalbe EC, Hayden JT, Rogers HA, Miller S, Lindsey JC, Hill RM, Nicholson SL, Kilday JP, Adamowicz-Brice M, Storer L, Jacques TS, Robson K, Lowe J, Williamson D, Grundy RG, Bailey S, Clifford SC. Schwalbe EC, et al. Among authors: grundy rg. Acta Neuropathol. 2013 Dec;126(6):943-6. doi: 10.1007/s00401-013-1206-6. Epub 2013 Nov 9. Acta Neuropathol. 2013. PMID: 24212602 Free PMC article. No abstract available.
Overcoming multiple drug resistance mechanisms in medulloblastoma.
Othman RT, Kimishi I, Bradshaw TD, Storer LC, Korshunov A, Pfister SM, Grundy RG, Kerr ID, Coyle B. Othman RT, et al. Among authors: grundy rg. Acta Neuropathol Commun. 2014 May 30;2:57. doi: 10.1186/2051-5960-2-57. Acta Neuropathol Commun. 2014. PMID: 24887326 Free PMC article.
Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours.
Haque F, Varlet P, Puntonet J, Storer L, Bountali A, Rahman R, Grill J, Carcaboso AM, Jones C, Layfield R, Grundy RG. Haque F, et al. Among authors: grundy rg. Acta Neuropathol Commun. 2017 Jun 6;5(1):45. doi: 10.1186/s40478-017-0449-1. Acta Neuropathol Commun. 2017. PMID: 28587626 Free PMC article.
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL, Brogan P, Jacques TS, Williams HJ, Martinez-Barbera JP. Apps JR, et al. Acta Neuropathol. 2018 May;135(5):757-777. doi: 10.1007/s00401-018-1830-2. Epub 2018 Mar 14. Acta Neuropathol. 2018. PMID: 29541918 Free PMC article.
Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours.
Bennett CD, Kohe SE, Gill SK, Davies NP, Wilson M, Storer LCD, Ritzmann T, Paine SML, Scott IS, Nicklaus-Wollenteit I, Tennant DA, Grundy RG, Peet AC. Bennett CD, et al. Among authors: grundy rg. Sci Rep. 2018 Aug 10;8(1):11992. doi: 10.1038/s41598-018-30342-8. Sci Rep. 2018. PMID: 30097636 Free PMC article.
Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste.
Smith SJ, Tyler BM, Gould T, Veal GJ, Gorelick N, Rowlinson J, Serra R, Ritchie A, Berry P, Otto A, Choi J, Skuli N, Estevez-Cebrero M, Shakesheff KM, Brem H, Grundy RG, Rahman R. Smith SJ, et al. Among authors: grundy rg. Clin Cancer Res. 2019 Aug 15;25(16):5094-5106. doi: 10.1158/1078-0432.CCR-18-3850. Epub 2019 May 21. Clin Cancer Res. 2019. PMID: 31113843
221 results