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Prolonged cultured human hepatocytes as an in vitro experimental system for the evaluation of potency and duration of activity of RNA therapeutics: Demonstration of prolonged duration of gene silencing effects of a GalNAc-conjugated human hypoxanthine phosphoribosyl transferase (HPRT1) siRNA.
Yang Q, Humphreys SC, Lade JM, Li AP. Yang Q, et al. Among authors: lade jm. Biochem Pharmacol. 2021 Jul;189:114374. doi: 10.1016/j.bcp.2020.114374. Epub 2020 Dec 30. Biochem Pharmacol. 2021. PMID: 33358826
34 results