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Serum amyloid P component and pro-platelet basic protein in extracellular vesicles or serum are novel markers of liver fibrosis in chronic hepatitis C patients.
Shirai K, Hikita H, Sakane S, Narumi R, Adachi J, Doi A, Tanaka S, Tahata Y, Yamada R, Kodama T, Sakamori R, Tatsumi T, Mita E, Tomonaga T, Takehara T. Shirai K, et al. Among authors: sakane s. PLoS One. 2022 Jul 7;17(7):e0271020. doi: 10.1371/journal.pone.0271020. eCollection 2022. PLoS One. 2022. PMID: 35797333 Free PMC article.
Administration of low-dose epoetin-alpha facilitates adherence to ribavirin in triple therapy with pegylated interferon-alpha-2b and telaprevir.
Ishida H, Sakane S, Toyama T, Fukutomi K, Kimura K, Sugimoto A, Hibino K, Tamura T, Iwasaki T, Iwasaki R, Hasegawa H, Sakakibara Y, Yamada T, Nakazuru S, Mita E. Ishida H, et al. Among authors: sakane s. Hepatol Res. 2014 Oct;44(10):E84-91. doi: 10.1111/hepr.12224. Epub 2014 Jan 7. Hepatol Res. 2014. PMID: 23957840
Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice.
Tanaka S, Hikita H, Tatsumi T, Sakamori R, Nozaki Y, Sakane S, Shiode Y, Nakabori T, Saito Y, Hiramatsu N, Tabata K, Kawabata T, Hamasaki M, Eguchi H, Nagano H, Yoshimori T, Takehara T. Tanaka S, et al. Among authors: sakane s. Hepatology. 2016 Dec;64(6):1994-2014. doi: 10.1002/hep.28820. Epub 2016 Oct 21. Hepatology. 2016. PMID: 27637015
Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production.
Myojin Y, Hikita H, Sugiyama M, Sasaki Y, Fukumoto K, Sakane S, Makino Y, Takemura N, Yamada R, Shigekawa M, Kodama T, Sakamori R, Kobayashi S, Tatsumi T, Suemizu H, Eguchi H, Kokudo N, Mizokami M, Takehara T. Myojin Y, et al. Among authors: sakane s. Gastroenterology. 2021 Apr;160(5):1741-1754.e16. doi: 10.1053/j.gastro.2020.12.015. Epub 2020 Dec 17. Gastroenterology. 2021. PMID: 33346004 Free article.
Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration.
Nozaki Y, Hikita H, Tanaka S, Fukumoto K, Urabe M, Sato K, Myojin Y, Doi A, Murai K, Sakane S, Saito Y, Kodama T, Sakamori R, Tatsumi T, Takehara T. Nozaki Y, et al. Among authors: sakane s. Sci Rep. 2021 Feb 9;11(1):3363. doi: 10.1038/s41598-021-83082-7. Sci Rep. 2021. PMID: 33564095 Free PMC article.
Gab1 in livers with persistent hepatocyte apoptosis has an antiapoptotic effect and reduces chronic liver injury, fibrosis, and tumorigenesis.
Mizutani N, Hikita H, Saito Y, Myojin Y, Sato K, Urabe M, Kurahashi T, Shiode Y, Sakane S, Murai K, Nozaki Y, Kodama T, Sakamori R, Yoshida Y, Tatsumi T, Takehara T. Mizutani N, et al. Among authors: sakane s. Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1;320(6):G958-G968. doi: 10.1152/ajpgi.00370.2020. Epub 2021 Mar 31. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33787344 Free article.
Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis.
Kozumi K, Kodama T, Murai H, Sakane S, Govaere O, Cockell S, Motooka D, Kakita N, Yamada Y, Kondo Y, Tahata Y, Yamada R, Hikita H, Sakamori R, Kamada Y, Daly AK, Anstee QM, Tatsumi T, Morii E, Takehara T. Kozumi K, et al. Among authors: sakane s. Hepatology. 2021 Nov;74(5):2452-2466. doi: 10.1002/hep.31995. Epub 2021 Aug 21. Hepatology. 2021. PMID: 34105780 Free PMC article.
White Adipose Tissue Autophagy and Adipose-Liver Crosstalk Exacerbate Nonalcoholic Fatty Liver Disease in Mice.
Sakane S, Hikita H, Shirai K, Myojin Y, Sasaki Y, Kudo S, Fukumoto K, Mizutani N, Tahata Y, Makino Y, Yamada R, Kodama T, Sakamori R, Tatsumi T, Takehara T. Sakane S, et al. Cell Mol Gastroenterol Hepatol. 2021;12(5):1683-1699. doi: 10.1016/j.jcmgh.2021.07.008. Epub 2021 Jul 22. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34303881 Free PMC article.
89 results