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119 results

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Using Human Induced Pluripotent Stem Cell-Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations.
Krishnamurthy M, Kechele DO, Broda T, Zhang X, Enriquez JR, McCauley HA, Sanchez JG, McCracken K, Palermo J, Bernieh A, Collins MH, Thomas IH, Neef HC, Heider A, Dauber A, Wells JM. Krishnamurthy M, et al. Among authors: sanchez jg. Gastroenterology. 2022 Oct;163(4):1053-1063.e7. doi: 10.1053/j.gastro.2022.06.083. Epub 2022 Jul 6. Gastroenterology. 2022. PMID: 35803312 Free PMC article.
Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells.
Eicher AK, Kechele DO, Sundaram N, Berns HM, Poling HM, Haines LE, Sanchez JG, Kishimoto K, Krishnamurthy M, Han L, Zorn AM, Helmrath MA, Wells JM. Eicher AK, et al. Among authors: sanchez jg. Cell Stem Cell. 2022 Jan 6;29(1):36-51.e6. doi: 10.1016/j.stem.2021.10.010. Epub 2021 Dec 1. Cell Stem Cell. 2022. PMID: 34856121 Free PMC article.
Enteroendocrine cell differentiation and function in the intestine.
Sanchez JG, Enriquez JR, Wells JM. Sanchez JG, et al. Curr Opin Endocrinol Diabetes Obes. 2022 Apr 1;29(2):169-176. doi: 10.1097/MED.0000000000000709. Curr Opin Endocrinol Diabetes Obes. 2022. PMID: 35066539 Free PMC article. Review.
Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation.
Pitstick AL, Poling HM, Sundaram N, Lewis PL, Kechele DO, Sanchez JG, Scott MA, Broda TR, Helmrath MA, Wells JM, Mayhew CN. Pitstick AL, et al. Among authors: sanchez jg. Stem Cell Reports. 2022 Aug 9;17(8):1889-1902. doi: 10.1016/j.stemcr.2022.06.011. Epub 2022 Jul 28. Stem Cell Reports. 2022. PMID: 35905739 Free PMC article.
Enteroendocrine Cells Protect the Stem Cell Niche by Regulating Crypt Metabolism in Response to Nutrients.
McCauley HA, Riedman AM, Enriquez JR, Zhang X, Watanabe-Chailland M, Sanchez JG, Kechele DO, Paul EF, Riley K, Burger C, Lang RA, Wells JM. McCauley HA, et al. Among authors: sanchez jg. Cell Mol Gastroenterol Hepatol. 2023;15(6):1293-1310. doi: 10.1016/j.jcmgh.2022.12.016. Epub 2023 Jan 4. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36608902 Free PMC article.
A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis.
Kang SY, Kimura M, Shrestha S, Lewis P, Lee S, Cai Y, Joshi P, Acharya P, Liu J, Yang Y, Sanchez JG, Ayyagari S, Alsberg E, Wells JM, Takebe T, Lee MY. Kang SY, et al. Among authors: sanchez jg. Adv Healthc Mater. 2024 Aug;13(21):e2302502. doi: 10.1002/adhm.202302502. Epub 2023 Sep 10. Adv Healthc Mater. 2024. PMID: 37616035
RFX6 regulates human intestinal patterning and function upstream of PDX1.
Sanchez JG, Rankin S, Paul E, McCauley HA, Kechele DO, Enriquez JR, Jones NH, Greeley SAW, Letourneau-Freiberg L, Zorn AM, Krishnamurthy M, Wells JM. Sanchez JG, et al. Development. 2024 Sep 15;151(18):dev204379. doi: 10.1242/dev.204379. Epub 2024 Sep 20. Development. 2024. PMID: 39302049 Free PMC article. No abstract available.
New Pioneers of Optogenetics in Neuroscience.
Somuncu ÖS, Berns HM, Sanchez JG. Somuncu ÖS, et al. Among authors: sanchez jg. Adv Exp Med Biol. 2020;1288:47-60. doi: 10.1007/5584_2019_473. Adv Exp Med Biol. 2020. PMID: 31983055 Review.
119 results