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Page 1
Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.
Titus HE, Xu H, Robinson AP, Patel PA, Chen Y, Fantini D, Eaton V, Karl M, Garrison ED, Rose IVL, Chiang MY, Podojil JR, Balabanov R, Liddelow SA, Miller RH, Popko B, Miller SD. Titus HE, et al. Among authors: garrison ed. Glia. 2022 Oct;70(10):1950-1970. doi: 10.1002/glia.24231. Epub 2022 Jul 9. Glia. 2022. PMID: 35809238 Free PMC article.
Induction of myelinating oligodendrocytes in human cortical spheroids.
Madhavan M, Nevin ZS, Shick HE, Garrison E, Clarkson-Paredes C, Karl M, Clayton BLL, Factor DC, Allan KC, Barbar L, Jain T, Douvaras P, Fossati V, Miller RH, Tesar PJ. Madhavan M, et al. Nat Methods. 2018 Sep;15(9):700-706. doi: 10.1038/s41592-018-0081-4. Epub 2018 Jul 25. Nat Methods. 2018. PMID: 30046099 Free PMC article.
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
Hubler Z, Allimuthu D, Bederman I, Elitt MS, Madhavan M, Allan KC, Shick HE, Garrison E, T Karl M, Factor DC, Nevin ZS, Sax JL, Thompson MA, Fedorov Y, Jin J, Wilson WK, Giera M, Bracher F, Miller RH, Tesar PJ, Adams DJ. Hubler Z, et al. Nature. 2018 Aug;560(7718):372-376. doi: 10.1038/s41586-018-0360-3. Epub 2018 Jul 25. Nature. 2018. PMID: 30046109 Free PMC article.
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity.
Clayton BLL, Kristell JD, Allan KC, Cohn EF, Karl M, Jerome AD, Garrison E, Maeno-Hikichi Y, Sturno AM, Kerr A, Shick HE, Sepeda JA, Freundt EC, Sas AR, Segal BM, Miller RH, Tesar PJ. Clayton BLL, et al. Nat Neurosci. 2024 Apr;27(4):656-665. doi: 10.1038/s41593-024-01580-z. Epub 2024 Feb 20. Nat Neurosci. 2024. PMID: 38378993 Free PMC article.