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Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.
Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Rivera GO, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, Denny TN, De Ussel MI, Satterwhite LL, Ko ER, Ginsburg GS, Kraft BD, Tsalik EL, Shen X, Woods CW. Giroux NS, et al. Among authors: ko er. Sci Rep. 2022 Jul 9;12(1):11714. doi: 10.1038/s41598-022-15668-8. Sci Rep. 2022. PMID: 35810186 Free PMC article.
Host gene expression classifiers diagnose acute respiratory illness etiology.
Tsalik EL, Henao R, Nichols M, Burke T, Ko ER, McClain MT, Hudson LL, Mazur A, Freeman DH, Veldman T, Langley RJ, Quackenbush EB, Glickman SW, Cairns CB, Jaehne AK, Rivers EP, Otero RM, Zaas AK, Kingsmore SF, Lucas J, Fowler VG Jr, Carin L, Ginsburg GS, Woods CW. Tsalik EL, et al. Among authors: ko er. Sci Transl Med. 2016 Jan 20;8(322):322ra11. doi: 10.1126/scitranslmed.aad6873. Sci Transl Med. 2016. PMID: 26791949 Free PMC article.
Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis.
Wang L, Ko ER, Gilchrist JJ, Pittman KJ, Rautanen A, Pirinen M, Thompson JW, Dubois LG, Langley RJ, Jaslow SL, Salinas RE, Rouse DC, Moseley MA, Mwarumba S, Njuguna P, Mturi N; Wellcome Trust Case Control Consortium 2; Kenyan Bacteraemia Study Group; Williams TN, Scott JA, Hill AV, Woods CW, Ginsburg GS, Tsalik EL, Ko DC. Wang L, et al. Among authors: ko dc, ko er. Sci Adv. 2017 Mar 8;3(3):e1602096. doi: 10.1126/sciadv.1602096. eCollection 2017 Mar. Sci Adv. 2017. PMID: 28345042 Free PMC article. Clinical Trial.
Validation of a host response test to distinguish bacterial and viral respiratory infection.
Lydon EC, Henao R, Burke TW, Aydin M, Nicholson BP, Glickman SW, Fowler VG, Quackenbush EB, Cairns CB, Kingsmore SF, Jaehne AK, Rivers EP, Langley RJ, Petzold E, Ko ER, McClain MT, Ginsburg GS, Woods CW, Tsalik EL. Lydon EC, et al. Among authors: ko er. EBioMedicine. 2019 Oct;48:453-461. doi: 10.1016/j.ebiom.2019.09.040. Epub 2019 Oct 17. EBioMedicine. 2019. PMID: 31631046 Free PMC article.
Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.
Tillekeratne LG, Suchindran S, Ko ER, Petzold EA, Bodinayake CK, Nagahawatte A, Devasiri V, Kurukulasooriya R, Nicholson BP, McClain MT, Burke TW, Tsalik EL, Henao R, Ginsburg GS, Reller ME, Woods CW. Tillekeratne LG, et al. Among authors: ko er. Open Forum Infect Dis. 2020 May 26;7(6):ofaa194. doi: 10.1093/ofid/ofaa194. eCollection 2020 Jun. Open Forum Infect Dis. 2020. PMID: 32617371 Free PMC article.
50 results