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Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.
Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Rivera GO, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, Denny TN, De Ussel MI, Satterwhite LL, Ko ER, Ginsburg GS, Kraft BD, Tsalik EL, Shen X, Woods CW. Giroux NS, et al. Among authors: sempowski gd. Sci Rep. 2022 Jul 9;12(1):11714. doi: 10.1038/s41598-022-15668-8. Sci Rep. 2022. PMID: 35810186 Free PMC article.
Regulation of T cell function by microRNA-720.
Wang Y, Zhang Z, Ji D, Chen GF, Feng X, Gong LL, Guo J, Li ZW, Chen CF, Zhao BB, Li ZG, Li QJ, Yan HP, Sempowski G, Wang FS, He YW. Wang Y, et al. Sci Rep. 2015 Jul 22;5:12159. doi: 10.1038/srep12159. Sci Rep. 2015. PMID: 26199080 Free PMC article.
Bayesian Multi-Plate High-Throughput Screening of Compounds.
Shterev ID, Dunson DB, Chan C, Sempowski GD. Shterev ID, et al. Among authors: sempowski gd. Sci Rep. 2018 Jun 22;8(1):9551. doi: 10.1038/s41598-018-27531-w. Sci Rep. 2018. PMID: 29934615 Free PMC article.
Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches.
McClain MT, Constantine FJ, Henao R, Liu Y, Tsalik EL, Burke TW, Steinbrink JM, Petzold E, Nicholson BP, Rolfe R, Kraft BD, Kelly MS, Sempowski GD, Denny TN, Ginsburg GS, Woods CW. McClain MT, et al. Among authors: sempowski gd. medRxiv [Preprint]. 2020 Jul 26:2020.07.20.20155507. doi: 10.1101/2020.07.20.20155507. medRxiv. 2020. Update in: Nat Commun. 2021 Feb 17;12(1):1079. doi: 10.1038/s41467-021-21289-y PMID: 32743603 Free PMC article. Updated. Preprint.
Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity.
Giroux NS, Ding S, McClain MT, Burke TW, Petzold E, Chung HA, Palomino GR, Wang E, Xi R, Bose S, Rotstein T, Nicholson BP, Chen T, Henao R, Sempowski GD, Denny TN, Ko ER, Ginsburg GS, Kraft BD, Tsalik EL, Woods CW, Shen X. Giroux NS, et al. Among authors: sempowski gd. bioRxiv [Preprint]. 2020 Dec 9:2020.12.04.412155. doi: 10.1101/2020.12.04.412155. bioRxiv. 2020. PMID: 33300002 Free PMC article. Preprint.
Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.
McClain MT, Constantine FJ, Henao R, Liu Y, Tsalik EL, Burke TW, Steinbrink JM, Petzold E, Nicholson BP, Rolfe R, Kraft BD, Kelly MS, Saban DR, Yu C, Shen X, Ko EM, Sempowski GD, Denny TN, Ginsburg GS, Woods CW. McClain MT, et al. Among authors: sempowski gd. Nat Commun. 2021 Feb 17;12(1):1079. doi: 10.1038/s41467-021-21289-y. Nat Commun. 2021. PMID: 33597532 Free PMC article.
Mucosal-associated invariant T cell responses differ by sex in COVID-19.
Yu C, Littleton S, Giroux NS, Mathew R, Ding S, Kalnitsky J, Yang Y, Petzold E, Chung HA, Rivera GO, Rotstein T, Xi R, Ko ER, Tsalik EL, Sempowski GD, Denny TN, Burke TW, McClain MT, Woods CW, Shen X, Saban DR. Yu C, et al. Among authors: sempowski gd. Med. 2021 Jun 11;2(6):755-772.e5. doi: 10.1016/j.medj.2021.04.008. Epub 2021 Apr 13. Med. 2021. PMID: 33870241 Free PMC article.
Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses.
Saunders KO, Lee E, Parks R, Martinez DR, Li D, Chen H, Edwards RJ, Gobeil S, Barr M, Mansouri K, Alam SM, Sutherland LL, Cai F, Sanzone AM, Berry M, Manne K, Bock KW, Minai M, Nagata BM, Kapingidza AB, Azoitei M, Tse LV, Scobey TD, Spreng RL, Rountree RW, DeMarco CT, Denny TN, Woods CW, Petzold EW, Tang J, Oguin TH 3rd, Sempowski GD, Gagne M, Douek DC, Tomai MA, Fox CB, Seder R, Wiehe K, Weissman D, Pardi N, Golding H, Khurana S, Acharya P, Andersen H, Lewis MG, Moore IN, Montefiori DC, Baric RS, Haynes BF. Saunders KO, et al. Among authors: sempowski gd. Nature. 2021 Jun;594(7864):553-559. doi: 10.1038/s41586-021-03594-0. Epub 2021 May 10. Nature. 2021. PMID: 33971664 Free PMC article.
204 results