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LIGHT (TNFSF14) Costimulation Enhances Myeloid Cell Activation and Antitumor Immunity in the Setting of PD-1/PD-L1 and TIGIT Checkpoint Blockade.
Yoo KJ, Johannes K, González LE, Patel A, Shuptrine CW, Opheim Z, Lenz K, Campbell K, Nguyen TA, Miriyala J, Smith C, McGuire A, Tsai YH, Rangwala F, de Silva S, Schreiber TH, Fromm G. Yoo KJ, et al. Among authors: johannes k. J Immunol. 2022 Aug 1;209(3):510-525. doi: 10.4049/jimmunol.2101175. Epub 2022 Jul 11. J Immunol. 2022. PMID: 35817517 Free PMC article.
Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy.
Fromm G, de Silva S, Johannes K, Patel A, Hornblower JC, Schreiber TH. Fromm G, et al. Among authors: johannes k. J Immunother Cancer. 2018 Dec 18;6(1):149. doi: 10.1186/s40425-018-0454-3. J Immunother Cancer. 2018. PMID: 30563566 Free PMC article.
Cutting Edge: Bispecific γδ T Cell Engager Containing Heterodimeric BTN2A1 and BTN3A1 Promotes Targeted Activation of Vγ9Vδ2+ T Cells in the Presence of Costimulation by CD28 or NKG2D.
Lai AY, Patel A, Brewer F, Evans K, Johannes K, González LE, Yoo KJ, Fromm G, Wilson K, Schreiber TH, de Silva S. Lai AY, et al. Among authors: johannes k. J Immunol. 2022 Oct 15;209(8):1475-1480. doi: 10.4049/jimmunol.2200185. Epub 2022 Sep 12. J Immunol. 2022. PMID: 36096643 Free PMC article.
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.
Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, Devoss JJ, Johannes KP, Lu W, Gardner J, Chang A, Bubulya P, Chang HY, Peterlin BM, Anderson MS. Su MA, et al. Among authors: johannes kp. J Clin Invest. 2008 May;118(5):1712-26. doi: 10.1172/JCI34523. J Clin Invest. 2008. PMID: 18414681 Free PMC article.
Deletional tolerance mediated by extrathymic Aire-expressing cells.
Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Gardner JM, et al. Science. 2008 Aug 8;321(5890):843-7. doi: 10.1126/science.1159407. Science. 2008. PMID: 18687966 Free PMC article.
40 results