Spotton K - Search Results

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Identification of an Optimized Clinical Development Candidate from Cilagicin, an Antibiotic That Evades Resistance by Dual Polyprenyl Phosphate Binding.

Rosenzweig A, Spotton K, Bhattacharjee A, Morales-Amador A, Brady SF. Rosenzweig A, et al. Among authors: spotton k. ACS Infect Dis. 2024 May 10;10(5):1536-1544. doi: 10.1021/acsinfecdis.4c00018. Epub 2024 Apr 16. ACS Infect Dis. 2024. PMID: 38626307 Free PMC article.

A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates.

Rosenzweig AF, Wang Z, Morales-Amador A, Spotton K, Brady SF. Rosenzweig AF, et al. Among authors: spotton k. ACS Infect Dis. 2023 Dec 8;9(12):2394-2400. doi: 10.1021/acsinfecdis.3c00475. Epub 2023 Nov 8. ACS Infect Dis. 2023. PMID: 37937847 Free PMC article.

Boron-Promoted Deprotonative Conjugate Addition: Geminal Diborons as Soft Pronucleophiles and Acyl Anion Equivalents.

Wang L, Lin S, Santos E, Pralat J, Spotton K, Sharma A. Wang L, et al. Among authors: spotton k. J Org Chem. 2022 Aug 5;87(15):9896-9906. doi: 10.1021/acs.joc.2c00914. Epub 2022 Jul 12. J Org Chem. 2022. PMID: 35819798 Free PMC article.

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