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Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ.
Kiourtis C, Terradas-Terradas M, Gee LM, May S, Georgakopoulou A, Collins AL, O'Sullivan ED, Baird DP, Hassan M, Shaw R, Tan EH, Müller M, Engelmann C, Andreola F, Hsieh YC, Reed LH, Borthwick LA, Nixon C, Clark W, Hanson PS, Sumpton D, Mackay G, Suzuki T, Najumudeen AK, Inman GJ, Campbell A, Barry ST, Quaglia A, Morris CM, LeBeau FEN, Sansom OJ, Kirschner K, Jalan R, Oakley F, Bird TG. Kiourtis C, et al. Among authors: hassan m. Nat Cell Biol. 2024 Dec;26(12):2075-2083. doi: 10.1038/s41556-024-01543-3. Epub 2024 Nov 13. Nat Cell Biol. 2024. PMID: 39537753 Free PMC article.
Attenuated fibrosis in specific pathogen-free microbiota in experimental cholestasis- and toxin-induced liver injury.
Moghadamrad S, Hassan M, McCoy KD, Kirundi J, Kellmann P, De Gottardi A. Moghadamrad S, et al. Among authors: hassan m. FASEB J. 2019 Nov;33(11):12464-12476. doi: 10.1096/fj.201901113R. Epub 2019 Aug 20. FASEB J. 2019. PMID: 31431085 Free PMC article.
In contrast to our hypothesis, these findings suggest that a complex intestinal microbiota may play a "hepato-protective" role.-Moghadamrad, S., Hassan, M., McCoy, K. D., Kirundi, J., Kellmann, P., De Gottardi, A. Attenuated fibrosis in specific pathogen-free microb …
In contrast to our hypothesis, these findings suggest that a complex intestinal microbiota may play a "hepato-protective" role.-Moghadamrad, …
Absence of gut microbiota impairs depletion of Paneth cells but not goblet cells in germ-free Atoh1lox/lox VilCreERT2 mice.
Hassan M, Juanola O, Huber S, Kellmann P, Zimmermann J, Lazzarini E, Ganal-Vonarburg SC, Gomez de Agüero M, Moghadamrad S. Hassan M, et al. Am J Physiol Gastrointest Liver Physiol. 2023 Jun 1;324(6):G426-G437. doi: 10.1152/ajpgi.00123.2022. Epub 2023 Mar 21. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36942864 Free article.
7,111 results