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ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors.
Rehman H, Chandrashekar DS, Balabhadrapatruni C, Nepal S, Balasubramanya SAH, Shelton AK, Skinner KR, Ma AH, Rao T, Agarwal S, Eich ML, Robinson AD, Naik G, Manne U, Netto GJ, Miller CR, Pan CX, Sonpavde G, Varambally S, Ferguson JE 3rd. Rehman H, et al. Among authors: agarwal s. JCI Insight. 2022 Aug 22;7(16):e155899. doi: 10.1172/jci.insight.155899. JCI Insight. 2022. PMID: 35852858 Free PMC article.
MicroRNA-101 regulated transcriptional modulator SUB1 plays a role in prostate cancer.
Chakravarthi BV, Goswami MT, Pathi SS, Robinson AD, Cieślik M, Chandrashekar DS, Agarwal S, Siddiqui J, Daignault S, Carskadon SL, Jing X, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S. Chakravarthi BV, et al. Among authors: agarwal s. Oncogene. 2016 Dec 8;35(49):6330-6340. doi: 10.1038/onc.2016.164. Epub 2016 Jun 6. Oncogene. 2016. PMID: 27270442 Free PMC article.
Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer.
Chakravarthi BV, Goswami MT, Pathi SS, Dodson M, Chandrashekar DS, Agarwal S, Nepal S, Hodigere Balasubramanya SA, Siddiqui J, Lonigro RJ, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S. Chakravarthi BV, et al. Among authors: agarwal s. Prostate. 2017 Jan;77(1):10-21. doi: 10.1002/pros.23243. Epub 2016 Aug 22. Prostate. 2017. PMID: 27550065 Free article.
miR-34a Regulates Expression of the Stathmin-1 Oncoprotein and Prostate Cancer Progression.
Chakravarthi BVSK, Chandrashekar DS, Agarwal S, Balasubramanya SAH, Pathi SS, Goswami MT, Jing X, Wang R, Mehra R, Asangani IA, Chinnaiyan AM, Manne U, Sonpavde G, Netto GJ, Gordetsky J, Varambally S. Chakravarthi BVSK, et al. Among authors: agarwal s. Mol Cancer Res. 2018 Jul;16(7):1125-1137. doi: 10.1158/1541-7786.MCR-17-0230. Epub 2017 Oct 12. Mol Cancer Res. 2018. PMID: 29025958 Free PMC article.
Expression and role of PAICS, a de novo purine biosynthetic gene in prostate cancer.
Chakravarthi BVSK, Goswami MT, Pathi SS, Dodson M, Chandrashekar DS, Agarwal S, Nepal S, Hodigere Balasubramanya SA, Siddiqui J, Lonigro RJ, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S. Chakravarthi BVSK, et al. Among authors: agarwal s. Prostate. 2018 Jun;78(9):693-694. doi: 10.1002/pros.23533. Epub 2018 Apr 10. Prostate. 2018. PMID: 29744932 Free article. No abstract available.
A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression.
Chakravarthi BVSK, Rodriguez Pena MDC, Agarwal S, Chandrashekar DS, Hodigere Balasubramanya SA, Jabboure FJ, Matoso A, Bivalacqua TJ, Rezaei K, Chaux A, Grizzle WE, Sonpavde G, Gordetsky J, Netto GJ, Varambally S. Chakravarthi BVSK, et al. Among authors: agarwal s. Neoplasia. 2018 Sep;20(9):894-904. doi: 10.1016/j.neo.2018.07.006. Epub 2018 Aug 15. Neoplasia. 2018. PMID: 30121007 Free PMC article.
7,185 results