Tan L - Search Results

1

Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.

Cheng L, Zhou S, Zhou S, Shi K, Cheng Y, Cai MC, Ye K, Lin L, Zhang Z, Jia C, Xiang H, Zang J, Zhang M, Yin X, Li Y, Di W, Zhuang G, Tan L. Cheng L, et al. Among authors: tan l. Cancer Res. 2022 Oct 4;82(19):3588-3602. doi: 10.1158/0008-5472.CAN-22-0222. Cancer Res. 2022. PMID: 35857807

2

Multiregion whole-genome sequencing depicts intratumour heterogeneity and punctuated evolution in ovarian clear cell carcinoma.

Yin X, Bi R, Ma P, Zhang S, Zhang Y, Sun Y, Zhang Y, Jing Y, Yu M, Wang W, Tan L, Di W, Zhuang G, Cai MC. Yin X, et al. Among authors: tan l. J Med Genet. 2020 Sep;57(9):605-609. doi: 10.1136/jmedgenet-2019-106418. Epub 2019 Dec 20. J Med Genet. 2020. PMID: 31862729

3

T-cell exhaustion interrelates with immune cytolytic activity to shape the inflamed tumor microenvironment.

Cai MC, Zhao X, Cao M, Ma P, Chen M, Wu J, Jia C, He C, Fu Y, Tan L, Xue X, Yu Z, Zhuang G. Cai MC, et al. Among authors: tan l. J Pathol. 2020 Jun;251(2):147-159. doi: 10.1002/path.5435. Epub 2020 May 19. J Pathol. 2020. PMID: 32222046

4

CDK12/13 inhibition induces immunogenic cell death and enhances anti-PD-1 anticancer activity in breast cancer.

Li Y, Zhang H, Li Q, Zou P, Huang X, Wu C, Tan L. Li Y, et al. Among authors: tan l. Cancer Lett. 2020 Dec 28;495:12-21. doi: 10.1016/j.canlet.2020.09.011. Epub 2020 Sep 15. Cancer Lett. 2020. PMID: 32941949

5

Baseline immunity and impact of chemotherapy on immune microenvironment in cervical cancer.

Zhang Y, Yu M, Jing Y, Cheng J, Zhang C, Cheng L, Lu H, Cai MC, Wu J, Wang W, Lou W, Qiu L, Tan L, Lu H, Yin X, Zhuang G, Di W. Zhang Y, et al. Among authors: tan l. Br J Cancer. 2021 Jan;124(2):414-424. doi: 10.1038/s41416-020-01123-w. Epub 2020 Oct 22. Br J Cancer. 2021. PMID: 33087896 Free PMC article.

6

Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.

Shan H, Liu J, Shen J, Dai J, Xu G, Lu K, Han C, Wang Y, Xu X, Tong Y, Xiang H, Ai Z, Zhuang G, Hu J, Zhang Z, Li Y, Pan L, Tan L. Shan H, et al. Among authors: tan l. Cell Chem Biol. 2021 Jun 17;28(6):855-865.e9. doi: 10.1016/j.chembiol.2021.04.020. Epub 2021 Apr 27. Cell Chem Biol. 2021. PMID: 33979649 Free PMC article.

7

SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer.

Lin L, Shi K, Zhou S, Cai MC, Zhang C, Sun Y, Zang J, Cheng L, Ye K, Ma P, Shen P, Zhang M, Cheng Y, Qi C, Li Y, Yin X, Zheng Y, Tan L, Zhuang G, Zang R. Lin L, et al. Among authors: tan l. Oncogene. 2022 Mar;41(12):1767-1779. doi: 10.1038/s41388-022-02210-3. Epub 2022 Feb 5. Oncogene. 2022. PMID: 35124696

8

Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer.

Tan L, Shan H, Han C, Zhang Z, Shen J, Zhang X, Xiang H, Lu K, Qi C, Li Y, Zhuang G, Chen G, Tan L. Tan L, et al. J Med Chem. 2022 Oct 27;65(20):13645-13659. doi: 10.1021/acs.jmedchem.2c00408. Epub 2022 Oct 11. J Med Chem. 2022. PMID: 36221183

9

Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads.

Wang J, Zhou S, Cheng Y, Cheng L, Qin Y, Zhang Z, Bi A, Xiang H, He X, Tian X, Liu W, Zhang J, Peng C, Zhu Z, Huang M, Li Y, Zhuang G, Tan L. Wang J, et al. Among authors: tan l. J Med Chem. 2023 Feb 23;66(4):2608-2621. doi: 10.1021/acs.jmedchem.2c01563. Epub 2023 Feb 1. J Med Chem. 2023. PMID: 36723914

10

Structural mechanism for specific binding of chemical compounds to amyloid fibrils.

Tao Y, Xia W, Zhao Q, Xiang H, Han C, Zhang S, Gu W, Tang W, Li Y, Tan L, Li D, Liu C. Tao Y, et al. Among authors: tan l. Nat Chem Biol. 2023 Oct;19(10):1235-1245. doi: 10.1038/s41589-023-01370-x. Epub 2023 Jul 3. Nat Chem Biol. 2023. PMID: 37400537

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