Leuthold MM - Search Results

1

Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases.

Kühl N, Lang J, Leuthold MM, Klein CD. Kühl N, et al. Among authors: leuthold mm. Eur J Med Chem. 2022 Oct 5;240:114585. doi: 10.1016/j.ejmech.2022.114585. Epub 2022 Jul 11. Eur J Med Chem. 2022. PMID: 35863275 Free PMC article.

2

De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease.

Nitsche C, Passioura T, Varava P, Mahawaththa MC, Leuthold MM, Klein CD, Suga H, Otting G. Nitsche C, et al. Among authors: leuthold mm. ACS Med Chem Lett. 2019 Jan 4;10(2):168-174. doi: 10.1021/acsmedchemlett.8b00535. eCollection 2019 Feb 14. ACS Med Chem Lett. 2019. PMID: 30783498 Free PMC article.

3

Prodrug Activation by a Viral Protease: Evaluating Combretastatin Peptide Hybrids To Selectively Target Infected Cells.

Richter M, Leuthold MM, Graf D, Bartenschlager R, Klein CD. Richter M, et al. Among authors: leuthold mm. ACS Med Chem Lett. 2019 Jul 18;10(8):1115-1121. doi: 10.1021/acsmedchemlett.9b00058. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413794 Free PMC article.

4

Peptide-β-lactam Inhibitors of Dengue and West Nile Virus NS2B-NS3 Protease Display Two Distinct Binding Modes.

Dražić T, Kopf S, Corridan J, Leuthold MM, Bertoša B, Klein CD. Dražić T, et al. Among authors: leuthold mm. J Med Chem. 2020 Jan 9;63(1):140-156. doi: 10.1021/acs.jmedchem.9b00759. Epub 2019 Dec 24. J Med Chem. 2020. PMID: 31804823 Free article.

5

Correction to Peptide-β-lactam Inhibitors of Dengue and West Nile Virus NS2B-NS3 Protease Display Two Distinct Binding Modes.

Dražić T, Kopf S, Corridan J, Leuthold MM, Bertoša B, Klein CD. Dražić T, et al. Among authors: leuthold mm. J Med Chem. 2020 Sep 24;63(18):10530. doi: 10.1021/acs.jmedchem.0c01358. Epub 2020 Sep 1. J Med Chem. 2020. PMID: 32871083 Free article. No abstract available.

6

Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture.

Kühl N, Leuthold MM, Behnam MAM, Klein CD. Kühl N, et al. Among authors: leuthold mm. J Med Chem. 2021 Apr 22;64(8):4567-4587. doi: 10.1021/acs.jmedchem.0c02042. Epub 2021 Apr 14. J Med Chem. 2021. PMID: 33851839

7

Efficiency Improvements and Discovery of New Substrates for a SARS-CoV-2 Main Protease FRET Assay.

Dražić T, Kühl N, Leuthold MM, Behnam MAM, Klein CD. Dražić T, et al. Among authors: leuthold mm. SLAS Discov. 2021 Oct;26(9):1189-1199. doi: 10.1177/24725552211020681. Epub 2021 Jun 19. SLAS Discov. 2021. PMID: 34151620 Free PMC article.

8

Antiviral drug discovery with an optimized biochemical dengue protease assay: Improved predictive power for antiviral efficacy.

Lang J, Dutta SK, Leuthold MM, Reichert L, Kühl N, Martina B, Klein CD. Lang J, et al. Among authors: leuthold mm. Antiviral Res. 2024 Dec 5;234:106053. doi: 10.1016/j.antiviral.2024.106053. Online ahead of print. Antiviral Res. 2024. PMID: 39645089 Free article.

9

Dual role of neddylation in transcription of hepatitis B virus RNAs from cccDNA and production of viral surface antigen.

Qu B, Nebioglu F, Leuthold MM, Ni Y, Mutz P, Beneke J, Erfle H, Vondran FWR, Bartenschlager R, Urban S. Qu B, et al. Among authors: leuthold mm. JHEP Rep. 2022 Aug 7;4(10):100551. doi: 10.1016/j.jhepr.2022.100551. eCollection 2022 Oct. JHEP Rep. 2022. PMID: 36124123 Free PMC article.

10

Structural Basis for Rabbit Hemorrhagic Disease Virus Antibody Specificity.

Leuthold MM, Kilic T, Devant JM, Landeta O, Parra F, Dalton KP, Hansman GS. Leuthold MM, et al. J Virol. 2022 Nov 23;96(22):e0121722. doi: 10.1128/jvi.01217-22. Epub 2022 Nov 3. J Virol. 2022. PMID: 36326275 Free PMC article.

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