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PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib.
Ding X, Zhu Z, Lapek J, McMillan EA, Zhang A, Chung CY, Dubbury S, Lapira J, Firdaus S, Kang X, Gao J, Oyer J, Chionis J, Rollins RA, Li L, Niessen S, Bagrodia S, Zhang L, VanArsdale T. Ding X, et al. Among authors: oyer j. Sci Rep. 2022 Jul 21;12(1):12501. doi: 10.1038/s41598-022-16623-3. Sci Rep. 2022. PMID: 35864202 Free PMC article.
Use of the dTAG system in vivo to degrade CDK2 and CDK5 in adult mice and explore potential safety liabilities.
Yenerall P, Sung T, Palyada K, Qian J, Arat S, Kumpf SW, Wang SW, Biddle K, Esparza C, Chang S, Scott W, Collette W, Winrow TS, Affolter T, Shirai N, Thibault S, Wang J, Liu L, Bauchmann M, Frey J, Steyn S, Sacaan A, Vitsky A, Ahn Y, Paul T, Lum L, Oyer J, Yang A, Hu W. Yenerall P, et al. Among authors: oyer j. Toxicol Sci. 2023 Jun 28;194(1):53-69. doi: 10.1093/toxsci/kfad049. Toxicol Sci. 2023. PMID: 37228089 Free PMC article.
Knockout of the inhibitory receptor TIGIT enhances the antitumor response of ex vivo expanded NK cells and prevents fratricide with therapeutic Fc-active TIGIT antibodies.
Hasan MF, Campbell AR, Croom-Perez TJ, Oyer JL, Dieffenthaller TA, Robles-Carrillo LD, Cash CA, Eloriaga JE, Kumar S, Andersen BW, Naeimi Kararoudi M, Tullius BP, Lee DA, Copik AJ. Hasan MF, et al. Among authors: oyer jl. J Immunother Cancer. 2023 Dec 11;11(12):e007502. doi: 10.1136/jitc-2023-007502. J Immunother Cancer. 2023. PMID: 38081778 Free PMC article.
TIGIT Expression on Activated NK Cells Correlates with Greater Anti-Tumor Activity but Promotes Functional Decline upon Lung Cancer Exposure: Implications for Adoptive Cell Therapy and TIGIT-Targeted Therapies.
Hasan MF, Croom-Perez TJ, Oyer JL, Dieffenthaller TA, Robles-Carrillo LD, Eloriaga JE, Kumar S, Andersen BW, Copik AJ. Hasan MF, et al. Among authors: oyer jl. Cancers (Basel). 2023 May 11;15(10):2712. doi: 10.3390/cancers15102712. Cancers (Basel). 2023. PMID: 37345049 Free PMC article.
microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling.
Noureddine S, Nie J, Schneider A, Menon V, Fliesen Z, Dhahbi J, Victoria B, Oyer J, Robles-Carrillo L, Nunes ADC, Ashiqueali S, Janusz A, Copik A, Robbins PD, Musi N, Masternak MM. Noureddine S, et al. Among authors: oyer j. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2213207120. doi: 10.1073/pnas.2213207120. Epub 2023 Mar 28. Proc Natl Acad Sci U S A. 2023. PMID: 36976763 Free PMC article.
39 results