Cohen SN - Search Results

1

Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes.

Deng N, Wu YY, Feng Y, Hsieh WC, Song JS, Lin YS, Tseng YH, Liao WJ, Chu YF, Liu YC, Chang EC, Liu CR, Sheu SY, Su MT, Kuo HC, Cohen SN, Cheng TH. Deng N, et al. Among authors: cohen sn. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204779119. doi: 10.1073/pnas.2204779119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914128 Free PMC article.

2

Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown.

Cheng HM, Chern Y, Chen IH, Liu CR, Li SH, Chun SJ, Rigo F, Bennett CF, Deng N, Feng Y, Lin CS, Yan YT, Cohen SN, Cheng TH. Cheng HM, et al. Among authors: cohen sn. PLoS Genet. 2015 Mar 11;11(3):e1005043. doi: 10.1371/journal.pgen.1005043. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25760041 Free PMC article.

3

DSIF modulates RNA polymerase II occupancy according to template G + C content.

Deng N, Zhang Y, Ma Z, Lin R, Cheng TH, Tang H, Snyder MP, Cohen SN. Deng N, et al. Among authors: cohen sn. NAR Genom Bioinform. 2022 Jul 27;4(3):lqac054. doi: 10.1093/nargab/lqac054. eCollection 2022 Sep. NAR Genom Bioinform. 2022. PMID: 35910045 Free PMC article.

4

Spt4 is selectively required for transcription of extended trinucleotide repeats.

Liu CR, Chang CR, Chern Y, Wang TH, Hsieh WC, Shen WC, Chang CY, Chu IC, Deng N, Cohen SN, Cheng TH. Liu CR, et al. Among authors: cohen sn. Cell. 2012 Feb 17;148(4):690-701. doi: 10.1016/j.cell.2011.12.032. Cell. 2012. PMID: 22341442 Free article.

5

Unpaired terminal nucleotides and 5' monophosphorylation govern 3' polyadenylation by Escherichia coli poly(A) polymerase I.

Feng Y, Cohen SN. Feng Y, et al. Among authors: cohen sn. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6415-20. doi: 10.1073/pnas.120173797. Proc Natl Acad Sci U S A. 2000. PMID: 10823925 Free PMC article.

6

The catalytic domain of RNase E shows inherent 3' to 5' directionality in cleavage site selection.

Feng Y, Vickers TA, Cohen SN. Feng Y, et al. Among authors: cohen sn. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14746-51. doi: 10.1073/pnas.202590899. Epub 2002 Nov 4. Proc Natl Acad Sci U S A. 2002. PMID: 12417756 Free PMC article.

7

Upregulation of the host SLC11A1 gene by Clostridium difficile toxin B facilitates glucosylation of Rho GTPases and enhances toxin lethality.

Feng Y, Cohen SN. Feng Y, et al. Among authors: cohen sn. Infect Immun. 2013 Aug;81(8):2724-32. doi: 10.1128/IAI.01177-12. Epub 2013 May 20. Infect Immun. 2013. PMID: 23690404 Free PMC article.

8

Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts.

Kramer NJ, Carlomagno Y, Zhang YJ, Almeida S, Cook CN, Gendron TF, Prudencio M, Van Blitterswijk M, Belzil V, Couthouis J, Paul JW 3rd, Goodman LD, Daughrity L, Chew J, Garrett A, Pregent L, Jansen-West K, Tabassian LJ, Rademakers R, Boylan K, Graff-Radford NR, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Boeve BF, Deng N, Feng Y, Cheng TH, Dickson DW, Cohen SN, Bonini NM, Link CD, Gao FB, Petrucelli L, Gitler AD. Kramer NJ, et al. Among authors: cohen sn. Science. 2016 Aug 12;353(6300):708-12. doi: 10.1126/science.aaf7791. Science. 2016. PMID: 27516603 Free PMC article.

9

Human MDM2 isoforms translated differentially on constitutive versus p53-regulated transcripts have distinct functions in the p53/MDM2 and TSG101/MDM2 feedback control loops.

Cheng TH, Cohen SN. Cheng TH, et al. Among authors: cohen sn. Mol Cell Biol. 2007 Jan;27(1):111-9. doi: 10.1128/MCB.00235-06. Epub 2006 Oct 23. Mol Cell Biol. 2007. PMID: 17060450 Free PMC article.

10

Identification of TSG101 functional domains and p21 loci required for TSG101-mediated p21 gene regulation.

Lin YS, Chen YJ, Cohen SN, Cheng TH. Lin YS, et al. Among authors: cohen sn. PLoS One. 2013 Nov 11;8(11):e79674. doi: 10.1371/journal.pone.0079674. eCollection 2013. PLoS One. 2013. PMID: 24244542 Free PMC article.

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