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Page 1
Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor.
Diaz E, Adhikary S, Tepper AWJW, Riley D, Ortiz-Meoz R, Krosky D, Buyck C, Lamenca CM, Llaveria J, Fang L, Kalin JH, Klaren VNA, Fahmy S, Shaffer PL, Kirkpatrick R, Carbajo RJ, Thomsen M, Impagliazzo A. Diaz E, et al. Among authors: buyck c. Commun Biol. 2022 Aug 5;5(1):787. doi: 10.1038/s42003-022-03735-9. Commun Biol. 2022. PMID: 35931745 Free PMC article.
Extending kinome coverage by analysis of kinase inhibitor broad profiling data.
Jacoby E, Tresadern G, Bembenek S, Wroblowski B, Buyck C, Neefs JM, Rassokhin D, Poncelet A, Hunt J, van Vlijmen H. Jacoby E, et al. Among authors: buyck c. Drug Discov Today. 2015 Jun;20(6):652-8. doi: 10.1016/j.drudis.2015.01.002. Epub 2015 Jan 14. Drug Discov Today. 2015. PMID: 25596550 Review.
A small-molecule fusion inhibitor of influenza virus is orally active in mice.
van Dongen MJP, Kadam RU, Juraszek J, Lawson E, Brandenburg B, Schmitz F, Schepens WBG, Stoops B, van Diepen HA, Jongeneelen M, Tang C, Vermond J, van Eijgen-Obregoso Real A, Blokland S, Garg D, Yu W, Goutier W, Lanckacker E, Klap JM, Peeters DCG, Wu J, Buyck C, Jonckers THM, Roymans D, Roevens P, Vogels R, Koudstaal W, Friesen RHE, Raboisson P, Dhanak D, Goudsmit J, Wilson IA. van Dongen MJP, et al. Among authors: buyck c. Science. 2019 Mar 8;363(6431):eaar6221. doi: 10.1126/science.aar6221. Science. 2019. PMID: 30846569 Free PMC article.
Identification of Z-Tyr-Ala-CHN2, a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2.
Doijen J, Temmerman K, Van den Eynde C, Diels A, Van den Broeck N, Van Gool M, Heo I, Jaensch S, Zwaagstra M, Diosa Toro M, Chiu W, De Jonghe S, Leyssen P, Bojkova D, Ciesek S, Cinatl J, Verschueren L, Buyck C, Van Kuppeveld F, Neyts J, Van Loock M, Van Damme E. Doijen J, et al. Among authors: buyck c. Microorganisms. 2023 Mar 10;11(3):717. doi: 10.3390/microorganisms11030717. Microorganisms. 2023. PMID: 36985290 Free PMC article.
Library enhancement through the wisdom of crowds.
Hack MD, Rassokhin DN, Buyck C, Seierstad M, Skalkin A, ten Holte P, Jones TK, Mirzadegan T, Agrafiotis DK. Hack MD, et al. Among authors: buyck c. J Chem Inf Model. 2011 Dec 27;51(12):3275-86. doi: 10.1021/ci200446y. Epub 2011 Nov 14. J Chem Inf Model. 2011. PMID: 22035213
Identification of novel inhibitors of rat Mrp3.
De Vocht T, Buyck C, Deferm N, Qi B, Van Brantegem P, van Vlijmen H, Snoeys J, Hoeben E, Vermeulen A, Annaert P. De Vocht T, et al. Among authors: buyck c. Eur J Pharm Sci. 2021 Jul 1;162:105813. doi: 10.1016/j.ejps.2021.105813. Epub 2021 Mar 19. Eur J Pharm Sci. 2021. PMID: 33753214
2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase.
Jonckers TH, Lin TI, Buyck C, Lachau-Durand S, Vandyck K, Van Hoof S, Vandekerckhove LA, Hu L, Berke JM, Vijgen L, Dillen LL, Cummings MD, de Kock H, Nilsson M, Sund C, Rydegård C, Samuelsson B, Rosenquist A, Fanning G, Van Emelen K, Simmen K, Raboisson P. Jonckers TH, et al. Among authors: buyck c. J Med Chem. 2010 Nov 25;53(22):8150-60. doi: 10.1021/jm101050a. Epub 2010 Oct 29. J Med Chem. 2010. PMID: 21033671
Potent peptidic fusion inhibitors of influenza virus.
Kadam RU, Juraszek J, Brandenburg B, Buyck C, Schepens WBG, Kesteleyn B, Stoops B, Vreeken RJ, Vermond J, Goutier W, Tang C, Vogels R, Friesen RHE, Goudsmit J, van Dongen MJP, Wilson IA. Kadam RU, et al. Among authors: buyck c. Science. 2017 Oct 27;358(6362):496-502. doi: 10.1126/science.aan0516. Epub 2017 Sep 28. Science. 2017. PMID: 28971971 Free PMC article.
20 results