Abourehab MAS - Search Results

1

Structure-guided approach on the role of substitution on amide-linked bipyrazoles and its effect on their anti-inflammatory activity.

Domiati SA, Abd El Galil KH, Abourehab MAS, Ibrahim TM, Ragab HM. Domiati SA, et al. Among authors: abourehab mas. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2179-2190. doi: 10.1080/14756366.2022.2109025. J Enzyme Inhib Med Chem. 2022. PMID: 35950562 Free PMC article.

2

Design, Synthesis, and Biological Evaluation of Some Novel Pyrrolizine Derivatives as COX Inhibitors with Anti-Inflammatory/Analgesic Activities and Low Ulcerogenic Liability.

Gouda AM, Ali HI, Almalki WH, Azim MA, Abourehab MA, Abdelazeem AH. Gouda AM, et al. Molecules. 2016 Feb 8;21(2):201. doi: 10.3390/molecules21020201. Molecules. 2016. PMID: 26867188 Free PMC article.

3

Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action.

Gouda AM, Abdelazeem AH, Omar HA, Abdalla AN, Abourehab MAS, Ali HI. Gouda AM, et al. Among authors: abourehab mas. Bioorg Med Chem. 2017 Oct 15;25(20):5637-5651. doi: 10.1016/j.bmc.2017.08.039. Epub 2017 Aug 24. Bioorg Med Chem. 2017. PMID: 28916158

4

Optimization of pyrrolizine-based Schiff bases with 4-thiazolidinone motif: Design, synthesis and investigation of cytotoxicity and anti-inflammatory potency.

Shawky AM, Abourehab MAS, Abdalla AN, Gouda AM. Shawky AM, et al. Among authors: abourehab mas. Eur J Med Chem. 2020 Jan 1;185:111780. doi: 10.1016/j.ejmech.2019.111780. Epub 2019 Oct 13. Eur J Med Chem. 2020. PMID: 31655429

5

Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities.

Attalah KM, Abdalla AN, Aslam A, Ahmed M, Abourehab MAS, ElSawy NA, Gouda AM. Attalah KM, et al. Among authors: abourehab mas. Bioorg Chem. 2020 Jan;94:103371. doi: 10.1016/j.bioorg.2019.103371. Epub 2019 Oct 24. Bioorg Chem. 2020. PMID: 31708230

6

Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities.

Shawky AM, Ibrahim NA, Abourehab MAS, Abdalla AN, Gouda AM. Shawky AM, et al. Among authors: abourehab mas. J Enzyme Inhib Med Chem. 2021 Dec;36(1):15-33. doi: 10.1080/14756366.2020.1837124. J Enzyme Inhib Med Chem. 2021. PMID: 33103497 Free PMC article.

7

Discovery of new pyrimidopyrrolizine/indolizine-based derivatives as P-glycoprotein inhibitors: Design, synthesis, cytotoxicity, and MDR reversal activities.

Shawky AM, Abdalla AN, Ibrahim NA, Abourehab MAS, Gouda AM. Shawky AM, et al. Among authors: abourehab mas. Eur J Med Chem. 2021 Jun 5;218:113403. doi: 10.1016/j.ejmech.2021.113403. Epub 2021 Mar 27. Eur J Med Chem. 2021. PMID: 33823396

8

Novel pyrrolizines bearing 3,4,5-trimethoxyphenyl moiety: design, synthesis, molecular docking, and biological evaluation as potential multi-target cytotoxic agents.

Shawky AM, Ibrahim NA, Abdalla AN, Abourehab MAS, Gouda AM. Shawky AM, et al. Among authors: abourehab mas. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1313-1333. doi: 10.1080/14756366.2021.1937618. J Enzyme Inhib Med Chem. 2021. PMID: 34154478 Free PMC article.

9

Pyrrolizine/Indolizine-NSAID Hybrids: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies.

Abourehab MAS, Alqahtani AM, Almalki FA, Zaher DM, Abdalla AN, Gouda AM, Beshr EAM. Abourehab MAS, et al. Molecules. 2021 Oct 30;26(21):6582. doi: 10.3390/molecules26216582. Molecules. 2021. PMID: 34770990 Free PMC article.

10

Design, synthesis, in vitro antiproliferative evaluation and in silico studies of new VEGFR-2 inhibitors based on 4-piperazinylquinolin-2(1H)-one scaffold.

Hassan A, Badr M, Abdelhamid D, Hassan HA, Abourehab MAS, Abuo-Rahma GEA. Hassan A, et al. Among authors: abourehab mas. Bioorg Chem. 2022 Mar;120:105631. doi: 10.1016/j.bioorg.2022.105631. Epub 2022 Jan 21. Bioorg Chem. 2022. PMID: 35091289

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