Cook GP - Search Results

1

TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8⁺ T cells.

Hope HC, Pickersgill G, Ginefra P, Vannini N, Cook GP, Salmond RJ. Hope HC, et al. Among authors: cook gp. Front Immunol. 2022 Jul 26;13:913184. doi: 10.3389/fimmu.2022.913184. eCollection 2022. Front Immunol. 2022. PMID: 35958566 Free PMC article.

2

Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity.

Wilson EB, El-Jawhari JJ, Neilson AL, Hall GD, Melcher AA, Meade JL, Cook GP. Wilson EB, et al. Among authors: cook gp. PLoS One. 2011;6(9):e22842. doi: 10.1371/journal.pone.0022842. Epub 2011 Sep 6. PLoS One. 2011. PMID: 21909397 Free PMC article.

3

Proteolytic activation of the cytotoxic phenotype during human NK cell development.

Meade JL, Wilson EB, Holmes TD, de Wynter EA, Brett P, Straszynski L, Ballard PA, Trapani JA, McDermott MF, Cook GP. Meade JL, et al. Among authors: cook gp. J Immunol. 2009 Jul 15;183(2):803-13. doi: 10.4049/jimmunol.0713829. Epub 2009 Jul 1. J Immunol. 2009. PMID: 19570824

4

Blocking oncogenic RAS enhances tumour cell surface MHC class I expression but does not alter susceptibility to cytotoxic lymphocytes.

El-Jawhari JJ, El-Sherbiny YM, Scott GB, Morgan RS, Prestwich R, Bowles PA, Blair GE, Tanaka T, Rabbitts TH, Meade JL, Cook GP. El-Jawhari JJ, et al. Among authors: cook gp. Mol Immunol. 2014 Apr;58(2):160-8. doi: 10.1016/j.molimm.2013.11.020. Epub 2013 Dec 22. Mol Immunol. 2014. PMID: 24365750 Free article.

5

Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma.

Close HJ, Stead LF, Nsengimana J, Reilly KA, Droop A, Wurdak H, Mathew RK, Corns R, Newton-Bishop J, Melcher AA, Short SC, Cook GP, Wilson EB. Close HJ, et al. Among authors: cook gp. Clin Exp Immunol. 2020 Apr;200(1):33-44. doi: 10.1111/cei.13403. Epub 2019 Dec 16. Clin Exp Immunol. 2020. PMID: 31784984 Free PMC article.

6

Oncolytic virus treatment differentially affects the CD56^dim and CD56^bright NK cell subsets in vivo and regulates a spectrum of human NK cell activity.

Wantoch M, Wilson EB, Droop AP, Phillips SL, Coffey M, El-Sherbiny YM, Holmes TD, Melcher AA, Wetherill LF, Cook GP. Wantoch M, et al. Among authors: cook gp. Immunology. 2022 May;166(1):104-120. doi: 10.1111/imm.13453. Epub 2022 Mar 9. Immunology. 2022. PMID: 35156714 Free PMC article.

7

Editorial: Factors determining long term anti-tumor responses to immune checkpoint blockade therapy.

Zappasodi R, Cook GP, Taylor A. Zappasodi R, et al. Among authors: cook gp. Front Immunol. 2022 Dec 21;13:1120207. doi: 10.3389/fimmu.2022.1120207. eCollection 2022. Front Immunol. 2022. PMID: 36618416 Free PMC article. No abstract available.

8

Pro- and anti-tumour activities of CD146/MCAM in breast cancer result from its heterogeneous expression and association with epithelial to mesenchymal transition.

Mannion AJ, Odell AF, Baker SM, Matthews LC, Jones PF, Cook GP. Mannion AJ, et al. Among authors: cook gp. Front Cell Dev Biol. 2023 Apr 17;11:1129015. doi: 10.3389/fcell.2023.1129015. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37138793 Free PMC article.

9

A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells.

Holmes TD, El-Sherbiny YM, Davison A, Clough SL, Blair GE, Cook GP. Holmes TD, et al. Among authors: cook gp. J Immunol. 2011 Feb 1;186(3):1538-45. doi: 10.4049/jimmunol.1000951. Epub 2010 Dec 29. J Immunol. 2011. PMID: 21191066

10

Controlled infection with a therapeutic virus defines the activation kinetics of human natural killer cells in vivo.

El-Sherbiny YM, Holmes TD, Wetherill LF, Black EV, Wilson EB, Phillips SL, Scott GB, Adair RA, Dave R, Scott KJ, Morgan RS, Coffey M, Toogood GJ, Melcher AA, Cook GP. El-Sherbiny YM, et al. Among authors: cook gp. Clin Exp Immunol. 2015 Apr;180(1):98-107. doi: 10.1111/cei.12562. Clin Exp Immunol. 2015. PMID: 25469725 Free PMC article. Clinical Trial.

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