Uesugi M - Search Results

1

Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers.

Hwang SY, Park S, Jo H, Hee Seo S, Jeon KH, Kim S, Jung AR, Song C, Ahn M, Yeon Kwak S, Lee HJ, Uesugi M, Na Y, Kwon Y. Hwang SY, et al. Among authors: uesugi m. J Adv Res. 2023 May;47:173-187. doi: 10.1016/j.jare.2022.08.003. Epub 2022 Aug 10. J Adv Res. 2023. PMID: 35963541 Free PMC article.

2

Wrenchnolol derivative optimized for gene activation in cells.

Jung D, Shimogawa H, Kwon Y, Mao Q, Sato S, Kamisuki S, Kigoshi H, Uesugi M. Jung D, et al. Among authors: uesugi m. J Am Chem Soc. 2009 Apr 8;131(13):4774-82. doi: 10.1021/ja900669k. J Am Chem Soc. 2009. PMID: 19290630

3

A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.

Kamisuki S, Mao Q, Abu-Elheiga L, Gu Z, Kugimiya A, Kwon Y, Shinohara T, Kawazoe Y, Sato S, Asakura K, Choo HY, Sakai J, Wakil SJ, Uesugi M. Kamisuki S, et al. Among authors: uesugi m. Chem Biol. 2009 Aug 28;16(8):882-92. doi: 10.1016/j.chembiol.2009.07.007. Chem Biol. 2009. PMID: 19716478 Free article.

4

A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction.

Shimogawa H, Kwon Y, Mao Q, Kawazoe Y, Choi Y, Asada S, Kigoshi H, Uesugi M. Shimogawa H, et al. Among authors: uesugi m. J Am Chem Soc. 2004 Mar 24;126(11):3461-71. doi: 10.1021/ja038855+. J Am Chem Soc. 2004. PMID: 15025473

5

Small molecule transcription factor mimic.

Kwon Y, Arndt HD, Mao Q, Choi Y, Kawazoe Y, Dervan PB, Uesugi M. Kwon Y, et al. Among authors: uesugi m. J Am Chem Soc. 2004 Dec 15;126(49):15940-1. doi: 10.1021/ja0445140. J Am Chem Soc. 2004. PMID: 15584709

6

Polyproline-rod approach to isolating protein targets of bioactive small molecules: isolation of a new target of indomethacin.

Sato S, Kwon Y, Kamisuki S, Srivastava N, Mao Q, Kawazoe Y, Uesugi M. Sato S, et al. Among authors: uesugi m. J Am Chem Soc. 2007 Jan 31;129(4):873-80. doi: 10.1021/ja0655643. J Am Chem Soc. 2007. PMID: 17243824

7

Intracellular Generation of a Diterpene-Peptide Conjugate that Inhibits 14-3-3-Mediated Interactions.

Parvatkar P, Kato N, Uesugi M, Sato S, Ohkanda J. Parvatkar P, et al. Among authors: uesugi m. J Am Chem Soc. 2015 Dec 23;137(50):15624-7. doi: 10.1021/jacs.5b09817. Epub 2015 Dec 9. J Am Chem Soc. 2015. PMID: 26632868

8

Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone.

Perron A, Nishikawa Y, Iwata J, Shimojo H, Takaya J, Kobayashi K, Imayoshi I, Mbenza NM, Takenoya M, Kageyama R, Kodama Y, Uesugi M. Perron A, et al. Among authors: uesugi m. J Biol Chem. 2018 May 25;293(21):8285-8294. doi: 10.1074/jbc.RA118.002316. Epub 2018 Mar 9. J Biol Chem. 2018. PMID: 29523683 Free PMC article.

9

Small-molecule fluorescent probes for specific RNA targets.

Murata A, Sato S, Kawazoe Y, Uesugi M. Murata A, et al. Among authors: uesugi m. Chem Commun (Camb). 2011 Apr 28;47(16):4712-4. doi: 10.1039/c1cc10393h. Epub 2011 Mar 17. Chem Commun (Camb). 2011. PMID: 21412566

10

Discovery of a Vitamin D Receptor-Silent Vitamin D Derivative That Impairs Sterol Regulatory Element-Binding Protein In Vivo.

Kawagoe F, Mendoza A, Hayata Y, Asano L, Kotake K, Mototani S, Kawamura S, Kurosaki S, Akagi Y, Takemoto Y, Nagasawa K, Nakagawa H, Uesugi M, Kittaka A. Kawagoe F, et al. Among authors: uesugi m. J Med Chem. 2021 May 13;64(9):5689-5709. doi: 10.1021/acs.jmedchem.0c02179. Epub 2021 Apr 24. J Med Chem. 2021. PMID: 33899473

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