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MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation.
Romero-Becerra R, Mora A, Manieri E, Nikolic I, Santamans AM, Montalvo-Romeral V, Cruz FM, Rodríguez E, León M, Leiva-Vega L, Sanz L, Bondía V, Filgueiras-Rama D, Jiménez-Borreguero LJ, Jalife J, Gonzalez-Teran B, Sabio G. Romero-Becerra R, et al. Elife. 2022 Aug 16;11:e75250. doi: 10.7554/eLife.75250. Elife. 2022. PMID: 35971771 Free PMC article.
Advanced Echocardiography With Left Atrial Strain and Indexed Left Atrial Three-Dimensional Volume for Predicting Underlying Atrial Fibrillation After Cryptogenic Stroke.
Vera A, Cecconi A, Ximénez-Carrillo Á, Ramos C, Martínez-Vives P, Lopez-Melgar B, Sanz-García A, Ortega G, Aguirre C, Vivancos J, Jiménez-Borreguero LJ, Alfonso F; DECRYTORING Study Investigators. Vera A, et al. Am J Cardiol. 2022 Dec 15;185:87-93. doi: 10.1016/j.amjcard.2022.09.004. Epub 2022 Oct 25. Am J Cardiol. 2022. PMID: 36307348
Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations.
Rivera-Torres J, Calvo CJ, Llach A, Guzmán-Martínez G, Caballero R, González-Gómez C, Jiménez-Borreguero LJ, Guadix JA, Osorio FG, López-Otín C, Herraiz-Martínez A, Cabello N, Vallmitjana A, Benítez R, Gordon LB, Jalife J, Pérez-Pomares JM, Tamargo J, Delpón E, Hove-Madsen L, Filgueiras-Rama D, Andrés V. Rivera-Torres J, et al. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7250-E7259. doi: 10.1073/pnas.1603754113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799555 Free PMC article.
Aging-Associated miR-217 Aggravates Atherosclerosis and Promotes Cardiovascular Dysfunction.
de Yébenes VG, Briones AM, Martos-Folgado I, Mur SM, Oller J, Bilal F, González-Amor M, Méndez-Barbero N, Silla-Castro JC, Were F, Jiménez-Borreguero LJ, Sánchez-Cabo F, Bueno H, Salaices M, Redondo JM, Ramiro AR. de Yébenes VG, et al. Arterioscler Thromb Vasc Biol. 2020 Oct;40(10):2408-2424. doi: 10.1161/ATVBAHA.120.314333. Epub 2020 Aug 27. Arterioscler Thromb Vasc Biol. 2020. PMID: 32847388 Free PMC article.
Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns.
Lucas E, Jurado-Pueyo M, Fortuño MA, Fernández-Veledo S, Vila-Bedmar R, Jiménez-Borreguero LJ, Lazcano JJ, Gao E, Gómez-Ambrosi J, Frühbeck G, Koch WJ, Díez J, Mayor F Jr, Murga C. Lucas E, et al. Biochim Biophys Acta. 2014 Dec;1842(12 Pt A):2448-56. doi: 10.1016/j.bbadis.2014.09.004. Epub 2014 Sep 18. Biochim Biophys Acta. 2014. PMID: 25239306 Free article.
Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
Gonzalez-Valdes I, Hidalgo I, Bujarrabal A, Lara-Pezzi E, Padron-Barthe L, Garcia-Pavia P, Gómez-del Arco P, Redondo JM, Ruiz-Cabello JM, Jimenez-Borreguero LJ, Enriquez JA, de la Pompa JL, Hidalgo A, Gonzalez S. Gonzalez-Valdes I, et al. Nat Commun. 2015 Mar 9;6:6473. doi: 10.1038/ncomms7473. Nat Commun. 2015. Retraction in: Nat Commun. 2017 Mar 07;8:14006. doi: 10.1038/ncomms14006. PMID: 25751743 Free PMC article. Retracted.
104 results