Abrams SI - Search Results

1

Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment.

Papadas A, Deb G, Cicala A, Officer A, Hope C, Pagenkopf A, Flietner E, Morrow ZT, Emmerich P, Wiesner J, Arauz G, Bansal V, Esbona K, Capitini CM, Matkowskyj KA, Deming DA, Politi K, Abrams SI, Harismendy O, Asimakopoulos F. Papadas A, et al. Among authors: abrams si. Cell Rep. 2022 Aug 16;40(7):111201. doi: 10.1016/j.celrep.2022.111201. Cell Rep. 2022. PMID: 35977482 Free PMC article.

2

Redirecting macrophage function to sustain their "defender" antitumor activity.

Tzetzo SL, Abrams SI. Tzetzo SL, et al. Among authors: abrams si. Cancer Cell. 2021 Jun 14;39(6):734-737. doi: 10.1016/j.ccell.2021.03.002. Epub 2021 Apr 1. Cancer Cell. 2021. PMID: 33798473 Free PMC article.

3

β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME.

Mohammadpour H, MacDonald CR, McCarthy PL, Abrams SI, Repasky EA. Mohammadpour H, et al. Among authors: abrams si. Cell Rep. 2021 Oct 26;37(4):109883. doi: 10.1016/j.celrep.2021.109883. Cell Rep. 2021. PMID: 34706232 Free PMC article.

4

Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence.

Dai T, Rosario SR, Katsuta E, Sawant Dessai A, Paterson EJ, Novickis AT, Cortes Gomez E, Zhu B, Liu S, Wang H, Abrams SI, Seshadri M, Bshara W, Dasgupta S. Dai T, et al. Among authors: abrams si. Cell Rep. 2022 Dec 6;41(10):111756. doi: 10.1016/j.celrep.2022.111756. Cell Rep. 2022. PMID: 36476868 Free PMC article.

5

Tumor-induced STAT3 signaling in myeloid cells impairs dendritic cell generation by decreasing PKCβII abundance.

Farren MR, Carlson LM, Netherby CS, Lindner I, Li PK, Gabrilovich DI, Abrams SI, Lee KP. Farren MR, et al. Among authors: abrams si. Sci Signal. 2014 Feb 18;7(313):ra16. doi: 10.1126/scisignal.2004656. Sci Signal. 2014. PMID: 24550541 Free PMC article.

6

Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis.

Brackett CM, Kojouharov B, Veith J, Greene KF, Burdelya LG, Gollnick SO, Abrams SI, Gudkov AV. Brackett CM, et al. Among authors: abrams si. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E874-83. doi: 10.1073/pnas.1521359113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831100 Free PMC article.

7

Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.

Singel KL, Emmons TR, Khan ANH, Mayor PC, Shen S, Wong JT, Morrell K, Eng KH, Mark J, Bankert RB, Matsuzaki J, Koya RC, Blom AM, McLeish KR, Qu J, Ram S, Moysich KB, Abrams SI, Odunsi K, Zsiros E, Segal BH. Singel KL, et al. Among authors: abrams si. JCI Insight. 2019 Mar 7;4(5):e122311. doi: 10.1172/jci.insight.122311. eCollection 2019 Mar 7. JCI Insight. 2019. PMID: 30730851 Free PMC article.

8

Myeloid-driven mechanisms as barriers to antitumor CD8⁺ T cell activity.

Colligan SH, Tzetzo SL, Abrams SI. Colligan SH, et al. Among authors: abrams si. Mol Immunol. 2020 Feb;118:165-173. doi: 10.1016/j.molimm.2019.12.012. Epub 2019 Dec 26. Mol Immunol. 2020. PMID: 31884388 Free PMC article. Review.

9

Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s.

Oba T, Long MD, Keler T, Marsh HC, Minderman H, Abrams SI, Liu S, Ito F. Oba T, et al. Among authors: abrams si. Nat Commun. 2020 Oct 27;11(1):5415. doi: 10.1038/s41467-020-19192-z. Nat Commun. 2020. PMID: 33110069 Free PMC article.

10

Breast Tumor Microenvironment in Black Women: A Distinct Signature of CD8+ T-Cell Exhaustion.

Yao S, Cheng TD, Elkhanany A, Yan L, Omilian A, Abrams SI, Evans S, Hong CC, Qi Q, Davis W, Liu S, Bandera EV, Odunsi K, Takabe K, Khoury T, Ambrosone CB. Yao S, et al. Among authors: abrams si. J Natl Cancer Inst. 2021 Aug 2;113(8):1036-1043. doi: 10.1093/jnci/djaa215. J Natl Cancer Inst. 2021. PMID: 33395700 Free PMC article.

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