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PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120.
Fazio G, Bresolin S, Silvestri D, Quadri M, Saitta C, Vendramini E, Buldini B, Palmi C, Bardini M, Grioni A, Rigamonti S, Galbiati M, Mecca S, Savino AM, Peloso A, Tu JW, Bhatia S, Borkhardt A, Micalizzi C, Lo Nigro L, Locatelli F, Conter V, Rizzari C, Valsecchi MG, Te Kronnie G, Biondi A, Cazzaniga G. Fazio G, et al. Among authors: palmi c. EBioMedicine. 2022 Sep;83:104224. doi: 10.1016/j.ebiom.2022.104224. Epub 2022 Aug 16. EBioMedicine. 2022. PMID: 35985167 Free PMC article.
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia.
Tartaglia M, Martinelli S, Cazzaniga G, Cordeddu V, Iavarone I, Spinelli M, Palmi C, Carta C, Pession A, Aricò M, Masera G, Basso G, Sorcini M, Gelb BD, Biondi A. Tartaglia M, et al. Among authors: palmi c. Blood. 2004 Jul 15;104(2):307-13. doi: 10.1182/blood-2003-11-3876. Epub 2004 Feb 24. Blood. 2004. PMID: 14982869 Free article.
TEL/ARG induces cytoskeletal abnormalities in 293T cells.
Palmi C, Fazio G, Cassetti A, Aloisi A, Villa A, Biondi A, Cazzaniga G. Palmi C, et al. Cancer Lett. 2006 Sep 8;241(1):79-86. doi: 10.1016/j.canlet.2005.10.017. Epub 2005 Nov 28. Cancer Lett. 2006. PMID: 16310306
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias.
Shochat C, Tal N, Bandapalli OR, Palmi C, Ganmore I, te Kronnie G, Cario G, Cazzaniga G, Kulozik AE, Stanulla M, Schrappe M, Biondi A, Basso G, Bercovich D, Muckenthaler MU, Izraeli S. Shochat C, et al. Among authors: palmi c. J Exp Med. 2011 May 9;208(5):901-8. doi: 10.1084/jem.20110580. Epub 2011 May 2. J Exp Med. 2011. PMID: 21536738 Free PMC article.
Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia.
Palmi C, Vendramini E, Silvestri D, Longinotti G, Frison D, Cario G, Shochat C, Stanulla M, Rossi V, Di Meglio AM, Villa T, Giarin E, Fazio G, Leszl A, Schrappe M, Basso G, Biondi A, Izraeli S, Conter V, Valsecchi MG, Cazzaniga G, Te Kronnie G. Palmi C, et al. Leukemia. 2012 Oct;26(10):2245-53. doi: 10.1038/leu.2012.101. Epub 2012 Apr 9. Leukemia. 2012. PMID: 22484421
Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups.
Attarbaschi A, Morak M, Cario G, Cazzaniga G, Ensor HM, te Kronnie T, Bradtke J, Mann G, Vendramini E, Palmi C, Schwab C, Russell LJ, Schrappe M, Conter V, Mitchell CD, Strehl S, Zimmermann M, Pötschger U, Harrison CJ, Stanulla M, Panzer-Grümayer R, Haas OA, Moorman AV; Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP)-Berlin-Frankfurt-Münster (BFM) Study Group and National Cancer Research Institute (NCRI)-Children's Cancer and Leukaemia (CCLG) Study Group. Attarbaschi A, et al. Among authors: palmi c. Br J Haematol. 2012 Sep;158(6):772-7. doi: 10.1111/j.1365-2141.2012.09221.x. Epub 2012 Jul 23. Br J Haematol. 2012. PMID: 22816614 Free article.
32 results