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Page 1
Missing lnc(RNAs) in Alzheimer's Disease?
Policarpo R, d'Ydewalle C. Policarpo R, et al. Genes (Basel). 2021 Dec 23;13(1):39. doi: 10.3390/genes13010039. Genes (Basel). 2021. PMID: 35052379 Free PMC article. Review.
From Junk to Function: LncRNAs in CNS Health and Disease.
Policarpo R, Sierksma A, De Strooper B, d'Ydewalle C. Policarpo R, et al. Front Mol Neurosci. 2021 Jul 19;14:714768. doi: 10.3389/fnmol.2021.714768. eCollection 2021. Front Mol Neurosci. 2021. PMID: 34349622 Free PMC article. Review.
Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor.
Ye Q, Shvartsbart A, Li Z, Gan P, Policarpo RL, Qi C, Roach JJ, Zhu W, McCammant MS, Hu B, Li G, Yin H, Carlsen P, Hoang G, Zhao L, Susick R, Zhang F, Lai CT, Allali Hassani A, Epling LB, Gallion A, Kurzeja-Lipinski K, Gallagher K, Roman V, Farren MR, Kong W, Deller MC, Zhang G, Covington M, Diamond S, Kim S, Yao W, Sokolsky A, Wang X. Ye Q, et al. Among authors: policarpo rl. J Med Chem. 2025 Jan 8. doi: 10.1021/acs.jmedchem.4c02662. Online ahead of print. J Med Chem. 2025. PMID: 39772605
The MIR-NAT MAPT-AS1 does not regulate Tau expression in human neurons.
Policarpo R, Wolfs L, Martínez-Montero S, Vandermeulen L, Royaux I, Van Peer G, Mestdagh P, De Strooper B, Sierksma A, d'Ydewalle C. Policarpo R, et al. PLoS One. 2025 Jan 6;20(1):e0314973. doi: 10.1371/journal.pone.0314973. eCollection 2025. PLoS One. 2025. PMID: 39761259 Free PMC article.
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.
Vandermeulen L, Geric I, Fumagalli L, Kreir M, Lu A, Nonneman A, Premereur J, Wolfs L, Policarpo R, Fattorelli N, De Bondt A, Van Den Wyngaert I, Asselbergh B, Fiers M, De Strooper B, d'Ydewalle C, Mancuso R. Vandermeulen L, et al. Among authors: policarpo r. Mol Neurodegener. 2024 Apr 24;19(1):37. doi: 10.1186/s13024-024-00725-9. Mol Neurodegener. 2024. PMID: 38654375 Free PMC article.
Asymmetric Total Synthesis of C9'-epi-Sinefungin.
Decultot L, Policarpo RL, Wright BA, Huang D, Shair MD. Decultot L, et al. Among authors: policarpo rl. Org Lett. 2020 Jul 17;22(14):5594-5599. doi: 10.1021/acs.orglett.0c01956. Epub 2020 Jul 6. Org Lett. 2020. PMID: 32628491
High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT).
Policarpo RL, Decultot L, May E, Kuzmič P, Carlson S, Huang D, Chu V, Wright BA, Dhakshinamoorthy S, Kannt A, Rani S, Dittakavi S, Panarese JD, Gaudet R, Shair MD. Policarpo RL, et al. J Med Chem. 2019 Nov 14;62(21):9837-9873. doi: 10.1021/acs.jmedchem.9b01238. Epub 2019 Oct 25. J Med Chem. 2019. PMID: 31589440 Free PMC article.
Flow-based enzymatic ligation by sortase A.
Policarpo RL, Kang H, Liao X, Rabideau AE, Simon MD, Pentelute BL. Policarpo RL, et al. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9203-8. doi: 10.1002/anie.201403582. Epub 2014 Jul 2. Angew Chem Int Ed Engl. 2014. PMID: 24989829
12 results