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Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.
Yenilmez B, Kelly M, Zhang GF, Wetoska N, Ilkayeva OR, Min K, Rowland L, DiMarzio C, He W, Raymond N, Lifshitz L, Pan M, Han X, Xie J, Friedline RH, Kim JK, Gao G, Herman MA, Newgard CB, Czech MP. Yenilmez B, et al. Among authors: lifshitz l. J Biol Chem. 2022 Oct;298(10):102401. doi: 10.1016/j.jbc.2022.102401. Epub 2022 Aug 18. J Biol Chem. 2022. PMID: 35988648 Free PMC article.
An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis.
Yenilmez B, Wetoska N, Kelly M, Echeverria D, Min K, Lifshitz L, Alterman JF, Hassler MR, Hildebrand S, DiMarzio C, McHugh N, Vangjeli L, Sousa J, Pan M, Han X, Brehm MA, Khvorova A, Czech MP. Yenilmez B, et al. Among authors: lifshitz l. Mol Ther. 2022 Mar 2;30(3):1329-1342. doi: 10.1016/j.ymthe.2021.11.007. Epub 2021 Nov 11. Mol Ther. 2022. PMID: 34774753 Free PMC article.
CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.
Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP. Tsagkaraki E, et al. Among authors: lifshitz lm. Nat Commun. 2021 Nov 26;12(1):6931. doi: 10.1038/s41467-021-27190-y. Nat Commun. 2021. PMID: 34836963 Free PMC article.
Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming.
Tsagkaraki E, Guilherme A, Nicoloro SM, Kelly M, Lifshitz LM, Wang H, Min K, Rowland LA, Santos KB, Wetoska N, Friedline RH, Maitland SA, Chen M, Weinstein LS, Wolfe SA, Kim JK, Czech MP. Tsagkaraki E, et al. Among authors: lifshitz lm. Mol Metab. 2023 Oct;76:101780. doi: 10.1016/j.molmet.2023.101780. Epub 2023 Jul 22. Mol Metab. 2023. PMID: 37482187 Free PMC article.
89 results